Tag: Agonist

For research use only. We do not sell to patients. α,β-Methylene-ATP dilithium CAS No. : 104809-20-3 Biological Activity：α,β-Methylene ATP dilithium, a phosphonic analog of ATP, is a P2X3 and P2X7 receptor ligand. α,β-Methylene ATP dilithium is a highly selective agonist for P2X1 and P2X3, with practically no activity at P2X2,4-7[2]. Research Area：Inflammation/Immunology Targets：P2X Receptor Related […]

For research use only. We do not sell to patients. Isotretinoin-d5 Biological Activity：Isotretinoin-d5 is the deuterium labeled Isotretinoin. Isotretinoin is an orally active vitamin A derivative and is often be used for the research of severe acne. Isotretinoin also shows anticancer activity[2][3]. Research Area：Cancer Targets：Autophagy|RAR/RXR|Endogenous Metabolite Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Nicotinamide N-oxide;3-Hydroxyglutaric acid-d5;DPPC-d62;SDMA-d6;2-Mercaptobenzothiazole;N-Acetyl-L-glutamic acid-d5;(3R,5S)-3-Hydroxy Cotinine-d3;Biliverdin […]

For research use only. We do not sell to patients. Histamine phosphate CAS No. : 51-74-1 Biological Activity：Histamine (phosphate) diphosphate is a potent agonist of histamine receptors and vasodilator. It can activate nitric oxide synthetase. Research Area：Neurological Disease|Endocrinology|Cancer Targets：Histamine Receptor|Endogenous Metabolite Related Screening Libraries:Natural Product Library Plus;Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug […]

For research use only. We do not sell to patients. 17α-Hydroxyprogesterone CAS No. : 68-96-2 Biological Activity：17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens. Research Area：Others Targets：Progesterone Receptor|Endogenous Metabolite Related Screening Libraries:Natural Product Library Plus; Drug […]

For research use only. We do not sell to patients. GPR30 agonist-1 CAS No. : 415919-74-3 Biological Activity：GPR30 agonist-1 is a G protein-coupled receptor 30 (GPR30) agonist. GPR30 agonist-1 exerts vasorelaxant effects. Research Area：Endocrinology|Cardiovascular Disease Targets：Estrogen Receptor/ERR Related Screening Libraries:Bioactive Compound Library Plus;Anti-Cardiovascular Disease Compound Library;Endocrinology Compound Library;Nuclear Receptor Compound Library; Related Small Molecules:DS20362725;LSD1/ER-IN-1;Giredestrant;Avobenzone;Estriol-d3;Chrysin;ERRγ Inverse […]

For research use only. We do not sell to patients. Allantoin CAS No. : 97-59-6 Biological Activity：Allantoin is a skin conditioning agent that promotes healthy skin, stimulates new and healthy tissue growth. Research Area：Cancer|Inflammation/Immunology Targets：Imidazoline Receptor|Endogenous Metabolite Related Screening Libraries:Natural Product Library Plus;Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library […]

For research use only. We do not sell to patients. IACS-8803 diammonium Biological Activity：IACS-8803 diammonium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 diammonium has a robust systemic antitumor efficacy. Research Area：Cancer Targets：STING Related Screening Libraries:Bioactive Compound Library Plus;Macrocyclic Compound Library; Related Small Molecules:STING agonist-3 trihydrochloride;BSP16;STING-IN-2;STING agonist-10;CDN-A;STING agonist-20;MSA-2;TAK-676;ADU-S100 ammonium salt;H-151;STING ligand-1;cGAMP;Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine;diABZI STING agonist-1;SR-717 […]

For research use only. We do not sell to patients. Hyodeoxycholic acid-d5 Biological Activity：Hyodeoxycholic acid-d5 (HDCA-d5) is the deuterium labeled Hyodeoxycholic acid. Hyodeoxycholic acid is a secondary bile acid formed in the small intestine by the gut flora, and acts as a TGR5 (GPCR19) agonist, with an EC50 of 31.6 µM in CHO cells. Research […]

For research use only. We do not sell to patients. Moxonidine hydrochloride CAS No. : 75536-04-8 Biological Activity：Moxonidine Hydrochloride is a selective agonist at the imidazoline receptor subtype 1, used as antihypertensive agent. Target: I1-R Moxonidine Hydrochloride is a centrally acting antihypertensive agent. Mixed Nischarin (I1 imidazoline receptor) and α2-AR (adrenergic) agonist; displays 40-fold higher […]

For research use only. We do not sell to patients. XL041 CAS No. : 1256918-39-4 Biological Activity：XL041 (BMS-852927) is an LXRβ-selective agonist. Research Area：Cardiovascular Disease Targets：LXR Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Clinical Compound Library;Anti-Cardiovascular Disease Compound Library;Lipid Metabolism Compound Library ;Targeted Diversity Library;Nuclear Receptor Compound Library; Related Small Molecules:BE1218;DMHCA;Saikosaponin A;27-Hydroxycholesterol;LXRβ […]