Tag: Agonist

For research use only. We do not sell to patients. PAMP-12 CAS No. : 929905-12-4 Biological Activity：PAMP-12 is a potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM). PAMP-12 is an endogenous peptide that elicit hypotension through inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffin cells. Research Area：Cardiovascular Disease Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole […]

For research use only. We do not sell to patients. Deltorphin 2 TFA Biological Activity：Deltorphin 2 TFA is a selective peptide agonist for the δ opioid receptor. Research Area：Neurological Disease Targets：Opioid Receptor Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;Neurotransmitter Receptor Compound Library;Peptide Library;Antidepressant Compound Library; Related Small Molecules:ORL1 antagonist 1;Loperamide-d6 […]

For research use only. We do not sell to patients. Wnt/β-catenin agonist 1 CAS No. : 2305372-67-0 Biological Activity：Wnt/β-catenin agonist 1 (compound 3f) is a Wnt/β-catenin signalling pathway agonist, with an EC50 of 0.27 μM. Research Area：Cancer Targets：Wnt Related Screening Libraries:Bioactive Compound Library Plus;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Reprogramming Compound […]

For research use only. We do not sell to patients. Calcitriol CAS No. : 32222-06-3 Biological Activity：Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist. Research Area：Cancer Targets：VD/VDR|Endogenous Metabolite Related Screening Libraries:Natural Product Library Plus;Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;Bioactive Compound Library Plus; Related Small […]

For research use only. We do not sell to patients. OptoBI-1 CAS No. : 2415272-11-4 Biological Activity：OptoBI-1 is a photochromic TRPC3 agonist, which asts as a photopharmacological tool to control of neuronal firing. Research Area：Neurological Disease Targets：TRP Channel Related Small Molecules:V116517;GSK2332255B;Pregnenolone monosulfate sodium;TRPC5-IN-4;SB-705498;TRPC3/6-IN-1;ABT-239;Pyr3;Asivatrep;Ononetin;TRPM8 antagonist 3;FEMA 4809;Hydroxy-α-sanshool;GsMTx4 TFA;TRPM4-IN-1;Palvanil;Pregnenolone monosulfate sodium-13C2,d2;Capsazepine;MSP-3;TRPM4-IN-2;Pregnenolone-d4-1;Umbellulone;Icilin;DS88790512;TRPV antagonist 1;ML-SA1 Trending products：Recombinant Proteins  |  […]

For research use only. We do not sell to patients. Quinolinic acid-d3 CAS No. : 138946-42-6 Biological Activity：Quinolinic acid-d3 is the deuterium labeled Quinolinic acid. Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction[2]. Research Area：Inflammation/Immunology|Neurological […]

For research use only. We do not sell to patients. RS 09 CAS No. : 1449566-36-2 Biological Activity：RS09 is a LPS peptide mimic serves as a candidate to be considered as a new class of TLR4 agonist adjuvant. RS09 increases antibody production in a vaccine setting. Research Area：Inflammation/Immunology Targets：Toll-like Receptor (TLR) Related Small Molecules:C29;TMX-201;ODN 20844;TLR7/8-IN-1;TLR8 […]

For research use only. We do not sell to patients. Omidenepag isopropyl CAS No. : 1187451-19-9 Biological Activity：Omidenepag isopropyl is a selective EP2 receptor agonist. Omidenepag isopropyl is converted to the active product Omidenepag during corneal penetration, and Omidenepag is a highly selective EP2 receptor agonist. Omidenepag isopropyl shows only weak affinity for EP1, EP2, and […]

For research use only. We do not sell to patients. LMD-009 CAS No. : 950195-51-4 Biological Activity：LMD-009 is a selective CCR8 nonpeptide agonist. LMD-009 mediates chemotaxis, inositol phosphate accumulation, and calcium release in high potencies with EC50s from 11 to 87 nM. Research Area：Metabolic Disease|Endocrinology Targets：CCR Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation […]

For research use only. We do not sell to patients. [Asn18] Endothelin-1, human CAS No. : 309245-97-4 Biological Activity：[Asn18] Endothelin-1, human is a peptide. Endothelin-1 is a major isoform of Endothelin and plays an important role for regulation of vascular function. Research Area：Cardiovascular Disease Targets：Endothelin Receptor Related Small Molecules:BQ-788;Endothelin-3, human, mouse, rabbit, rat TFA;IRL 2500;Sarafotoxin […]