Tag: Agonist

For research use only. We do not sell to patients. Sarafotoxin S6c CAS No. : 121695-87-2 Biological Activity：Sarafotoxin S6c (SRTX-c) is a potent endothelin-B receptor agonist. Sarafotoxin S6c can cause vasoconstriction in both endothelium-intact and endothelium-denuded vessels. Research Area：Cardiovascular Disease Targets：Endothelin Receptor Related Small Molecules:BQ-788;[Asn18] Endothelin-1, human;Endothelin-3, human, mouse, rabbit, rat TFA;IRL 2500;Sarafotoxin S6a;ANP (1-30), […]

For research use only. We do not sell to patients. Miltirone CAS No. : 27210-57-7 Biological Activity：Miltirone is a natural compound present in the root of Salvia miltiorrhiza. Miltirone is a central benzodiazepine receptor partial agonist, with an IC50 of 0.3 μM. Research Area：Neurological Disease Targets：GABA Receptor Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library […]

For research use only. We do not sell to patients. FPR2 agonist 2 Biological Activity：FPR2 agonist 2 is a potent and permeates the blood−brain barrier FPR2 agonist with an EC50 of 0.13 µM, 1.1 µM for FPR2 and FPR1, respectively. FPR2 agonist 2 inhibits the production of pro-inflammatory cytokines, counterbalances the changes in mitochondrial function, […]

For research use only. We do not sell to patients. Isoprenaline hydrochloride CAS No. : 51-30-9 Biological Activity：Isoprenaline (Isoproterenol) hydrochloride is a non-selective, orally active β-adrenergic receptor agonist. Isoprenaline has potent peripheral vasodilator, bronchodilator, and cardiac stimulating activities. Isoprenaline can be used for the research of bradycardia and bronchial asthma[2][3][4][5][6]. Research Area：Cardiovascular Disease|Endocrinology Targets：Adrenergic Receptor|Endogenous […]

For research use only. We do not sell to patients. Trimebutine-d5 fumarate CAS No. : 2747915-18-8 Biological Activity：Trimebutine-d5 (fumarate) is deuterium labeled Trimebutine. Research Area：Metabolic Disease Targets：Opioid Receptor Related Small Molecules:ORL1 antagonist 1;Loperamide-d6 N-Oxide;Deltorphin 2 TFA;Nalfurafine;β-Lipotropin (60-65);GSK1521498 free base;Dynorphin B (1-13) (TFA);Dermorphin Analog;β-Endorphin (6-31), human;JTC-801;Valorphin;Corydaline;TAN-452;Matrine;Naloxonazine dihydrochloride;[Leu5]-Enkephalin;Sec-O-Glucosylhamaudol;DPDPE;EST73502;CTOP;β-Endorphin, equine;Tyr-W-MIF-1;Nociceptin (1-13), amide TFA;Morphiceptin;[Nphe1]Nociceptin(1-13)NH2;UFP-101 Trending products：Recombinant Proteins  |  Bioactive […]

For research use only. We do not sell to patients. Resomelagon CAS No. : 1809420-71-0 Biological Activity：Resomelagon (AP1189) is a potent, orally active melanocortin receptor (MR) agonist about MC1 and MC3. Resomelagon induces ERK1/2 phosphorylation and Ca2+ mobilization. Resomelagon has anti-inflammatory activity. Resomelagon can be used for obesity and chronic inflammation research[2]. Research Area：Metabolic Disease|Inflammation/Immunology […]

For research use only. We do not sell to patients. S1P1 agonist III CAS No. : 1324003-64-6 Biological Activity：S1P1 Agonist III is a potent and orally active S1P1 agonist with EC50 of 18 nM; no activity on S1P3. IC50 value: 18 nM(EC50) [1] Target: S1P1 agonist When dosed orally at 1 and 3 mg/kg, the […]

For research use only. We do not sell to patients. VUF11207 fumarate CAS No. : 1785665-61-3 Biological Activity：VUF11207 fumarate is a CXCR7 agonist that binds specifically to CXCR7. VUF11207 fumarate reduces CXCL12-mediated osteoclastogenesis and bone resorption by inhibiting ERK phosphorylation. Research Area：Cancer|Inflammation/Immunology Targets：CXCR Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Anti-Cancer Compound […]

For research use only. We do not sell to patients. Alclometasone CAS No. : 67452-97-5 Biological Activity：Alclometasone (7a-Chloro-16a-methyl prednisolone) is a glucocorticoid and inhibits the release of pro-inflammatory mediators from leukocytes. Alclometasone can be used to relieve corticosteroid-responsive dermatoses, including atopic dermatitis, eczema, psoriasis and allergic dermatitis. Research Area：Inflammation/Immunology Targets：Glucocorticoid Receptor Related Small Molecules:Deflazacort-D5;Glucocorticoid receptor agonist-2;AZD2906;Beclometasone […]

For research use only. We do not sell to patients. Adipiplon CAS No. : 840486-93-3 Biological Activity：Adipiplon (NG2-73) is a selective GABAA receptor positive allosteric modulator. Adipiplon is particularly useful in the treatment of a variety of central nervous system (CNS) disorders. Research Area：Neurological Disease Targets：GABA Receptor Related Small Molecules:SKF89976A hydrochloride;mGAT-IN-1;Alpidem;FG8119;Valerenic acid;Picrotoxinin;Miltirone;Etifoxine-13C,d3;Gabazine;Broflanilide;Fluxametamide;ONO-8590580;γ-Aminobutyric acid-d6;Ginsenoside Rc;Fipronil;p-Hydroxybenzaldehyde-13C;Lesogaberan hydrochloride;FG […]