Tag: Activator|Inhibitor

For research use only. We do not sell to patients. WHI-P154 CAS No. : 211555-04-3 Biological Activity：WHI-P154 is a potent EGFR inhibitor, and also modestly blocks JAK3, with IC50s of 4 nM and 1.8 μM, respectively. Research Area：Cancer Targets：EGFR|JAK|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Epigenetics Compound Library;Immunology/Inflammation Compound Library;JAK/STAT Compound Library;Kinase Inhibitor Library;Protein […]

For research use only. We do not sell to patients. Oxiconazole CAS No. : 64211-45-6 Biological Activity：Oxiconazole (Ro 13-8996) is a broad spectrum anti-fungal agent which can inhibit the growth of Candida, Aspergillus and Trichophyton. Oxiconazole is also a highly efficacious activator of CYP3A4 transactivation, which could be antagonized by Rifampicin (HY-B0272) in a competitive […]

For research use only. We do not sell to patients. S2157 CAS No. : 2262488-39-9 Biological Activity：S2157, a N-alkylated tranylcypromine (TCP) derivative, is a potent lysine-specific demethylase 1 (LSD1) inhibitor. S2157 increases H3K9 methylation and reciprocal H3K27 deacetylation at super-enhancer regions. S2157 induces apoptosis in TCP-resistant T-cell acute lymphoblastic leukemia (T-ALL) cells by repressing transcription […]

For research use only. We do not sell to patients. GS-444217 CAS No. : 1262041-49-5 Biological Activity：GS-444217 is a potent, orally available and selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 of 2.87 nM. Research Area：Cancer Targets：MAP3K|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;MAPK Compound Library;Anti-Cancer […]

For research use only. We do not sell to patients. Thailanstatin D CAS No. : 1609105-89-6 Biological Activity：Thailanstatin D, an analogue of Thailanstatin A, is able to inhibit AR-V7 gene splicing by interfering the interaction between U2AF65 and SAP155 and preventing them from binding to polypyrimidine tract located between the branch point and the 3′ […]

For research use only. We do not sell to patients. Phillyrin CAS No. : 487-41-2 Biological Activity：Phillyrin is isolated from Forsythia suspensa Vahl (Oleaceae), has antibacterial and anti-inflammatory activities. Phillyrin has potential inductive effects on rat CYP1A2 and CYP2D1 activities, without affecting CYP2C11 and CYP3A1/2 activities. Phillyrin has anti-influenza A virus activities[2]. Research Area：Cancer|Infection|Inflammation/Immunology Targets：Influenza […]

For research use only. We do not sell to patients. BAY 11-7085 CAS No. : 196309-76-9 Biological Activity：BAY 11-7085 (BAY 11-7083) is an inhibitor of NF-κB activation and phosphorylation of IκBα; it stabilizes IκBα with an IC50 of 10 μM. Research Area：Cancer Targets：Ferroptosis|NF-κB|Apoptosis Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound […]

For research use only. We do not sell to patients. AZD1208 hydrochloride CAS No. : 1621866-96-3 Biological Activity：AZD1208 hydrochloride is an orally bioavailable, highly selective PIM kinases inhibitor. Research Area：Cancer Targets：Autophagy|Pim|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine D;STAT3-IN-10;Rigosertib sodium Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural […]

For research use only. We do not sell to patients. Dithianon CAS No. : 3347-22-6 Biological Activity：Dithianon is a broad-spectrum anthraquinone fungicide with good adherence to the surface of leaves and fruits. Dithianon is used to control several several fungal of some fruits and vegetables, as anthracnose (Colletotrichum sp., Elsinoe ampelina), mildew (Plasmopara viticola), phomopsis […]

For research use only. We do not sell to patients. Erlotinib CAS No. : 183321-74-6 Biological Activity：Erlotinib (CP-358774) is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment […]