Tag: Activator|Inhibitor

For research use only. We do not sell to patients. D-erythro-Sphingosine-d7 CAS No. : 1246304-34-6 Biological Activity：D-erythro-Sphingosine-d7 (Erythrosphingosine-d7) is the deuterium labeled D-erythro-Sphingosine. D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator[2][3][4]. Research Area：Cancer Targets：PKC|Phosphatase|Endogenous Metabolite […]

For research use only. We do not sell to patients. Thienopyridone CAS No. : 1018454-97-1 Biological Activity：Thienopyridone is a potent and selective phosphatase of regenerating liver (PRL) phosphatase inhibitor with IC50s of 173 nM, 277 nM and 128 nM for PRL-1, PRL-2, and PRL-3, respectively. Thienopyridone shows minimal effects on other phosphatases. Thienopyridone induces p130Cas […]

For research use only. We do not sell to patients. Oxiconazole nitrate CAS No. : 64211-46-7 Biological Activity：Oxiconazole (Ro 13-8996) nitrate is a broad spectrum anti-fungal agent which can inhibit the growth of Candida, Aspergillus and Trichophyton. Oxiconazole nitrate is also a highly efficacious activator of CYP3A4 transactivation, which could be antagonized by Rifampicin (HY-B0272) […]

For research use only. We do not sell to patients. Artefenomel CAS No. : 1029939-86-3 Biological Activity：Artefenomel (OZ439) is an orally active, synthetic anti-malarial compound containing an artemisinin pharmacophore with a mechanism of action similar to that of artemisinin. Artefenomel has antiviral activity against SARS-CoV-2[2]. Research Area：Infection Targets：Parasite|Ferroptosis|SARS-CoV Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical […]

For research use only. We do not sell to patients. HA15 CAS No. : 1609402-14-3 Biological Activity：HA15 is a potent and specific inhibitor of ER chaperone BiP/GRP78/HSPA5, inhibits the ATPase activity of BiP, with anti-cancerous activity. Research Area：Cancer Targets：Autophagy|HSP|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Autophagy […]

For research use only. We do not sell to patients. BMS-536924 CAS No. : 468740-43-4 Biological Activity：BMS-536924 is an orally active, competitive and selective insulin-like growth factor receptor (IGF-1R) kinase and insulin receptor (IR) inhibitor with IC50s of 100 nM and 73 nM, respectively. BMS-536924 has anti-cancer activity[2]. Research Area：Cancer|Endocrinology Targets：Insulin Receptor|IGF-1R|Apoptosis Related Screening Libraries:Bioactive […]

For research use only. We do not sell to patients. PF-4989216 CAS No. : 1276553-09-3 Biological Activity：PF-4989216 is a potent and selective PI3Kα inhibitor with a Ki of 0.6 nM. Research Area：Cancer Targets：Apoptosis|PI3K Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Differentiation […]

For research use only. We do not sell to patients. LJH685 CAS No. : 1627710-50-2 Biological Activity：LJH685 is a potent, ATP-competitive and selective RSK inhibitor, inhibits RSK1, 2, and 3 biochemical activities with IC50s of 6, 5, 4 nM, respectively. Research Area：Cancer Targets：Ribosomal S6 Kinase (RSK)|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound […]

For research use only. We do not sell to patients. PF-04691502 CAS No. : 1013101-36-4 Biological Activity：PF-04691502 is a potent and selective inhibitor of PI3K and mTOR. PF-04691502 binds to human PI3Kα, β, δ, γ and mTOR with Kis of 1.8, 2.1, 1.6, 1.9 and 16 nM, respectively. Research Area：Cancer Targets：Autophagy|mTOR|PI3K Related Screening Libraries:Drug Repurposing […]

For research use only. We do not sell to patients. HO-3867 CAS No. : 1172133-28-6 Biological Activity：HO-3867 is a selective and potent STAT3 inhibitor and shows good antitumor activity. Research Area：Cancer Targets：STAT|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound Library;JAK/STAT Compound Library;Kinase Inhibitor Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Small Molecule Immuno-Oncology Compound […]