Tag: Activator|Inhibitor

For research use only. We do not sell to patients. Tivantinib CAS No. : 905854-02-6 Biological Activity：Tivantinib is a highly selective c-Met tyrosine kinase inhibitor with a Ki of 355 nM. Research Area：Cancer Targets：c-Met/HGFR|Apoptosis Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer […]

For research use only. We do not sell to patients. Convallatoxin CAS No. : 508-75-8 Biological Activity：Convallatoxin is a cardiac glycoside isolated from Adonis amurensis Regel et Radde. Convallatoxin ameliorates colitic inflammation via activation of PPARγ and suppression of NF-κB. Convallatoxin is a P-glycoprotein (P-gp) substrate and recognized Val982 as an important amino acid involved […]

For research use only. We do not sell to patients. ARS-853 CAS No. : 1629268-00-3 Biological Activity：ARS-853 is a cell-active, selective, covalent KRAS G12C inhibitor with an IC50 of 2.5 μM. ARS-853 inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation[2]. Research Area：Cancer Targets：Apoptosis|Ras Related Screening Libraries:Bioactive Compound Library Plus; Related […]

For research use only. We do not sell to patients. Pictilisib CAS No. : 957054-30-7 Biological Activity：Pictilisib (GDC-0941) is a potent inhibitor of PI3Kα/δ with an IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold). Research Area：Cancer Targets：Autophagy|Apoptosis|PI3K Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis […]

For research use only. We do not sell to patients. UNC0638 CAS No. : 1255580-76-7 Biological Activity：UNC0638 selectively inhibits G9a and GLP histone methyltransferase activity with IC50s of less than 15 nM and 19 nM, respectively. UNC0638 has anti-FMDV (foot-and-mouth disease virus) and anti-VSV (vesicular stomatitis virus) activities. Research Area：Cancer|Infection Targets：Autophagy|Influenza Virus|Histone Methyltransferase Related Screening […]

For research use only. We do not sell to patients. QTX125 CAS No. : 1279698-31-5 Biological Activity：QTX125 is a potent and highly selective HDAC6 inhibitor. QTX125 exhibits excellent selectivity over other HDACs. QTX125 has antitumor effects. Research Area：Cancer Targets：HDAC|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine D;STAT3-IN-10;Rigosertib sodium Trending […]

For research use only. We do not sell to patients. Monastrol CAS No. : 329689-23-8 Biological Activity：Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5 with an IC50 value of 14 μM. Research Area：Cancer Targets：Kinesin|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Cytoskeleton Compound […]

For research use only. We do not sell to patients. Momelotinib sulfate CAS No. : 1056636-06-6 Biological Activity：Momelotinib sulfate (CYT387 sulfate salt) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, 10-fold selectivity versus JAK3 (IC50=155 nM). Research Area：Cancer Targets：JAK|Autophagy|Apoptosis Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library […]

For research use only. We do not sell to patients. S130 CAS No. : 1160852-22-1 Biological Activity：S130 is a high affinity, selective inhibitor of ATG4B (a major cysteine protease) with an IC50 of 3.24 µM. S130 suppresses autophagy flux. Research Area：Cancer Targets：Cathepsin|Autophagy|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Autophagy Compound […]

For research use only. We do not sell to patients. FX1 CAS No. : 1426138-42-2 Biological Activity：FX1 is a potent and specific BCL6 inhibitor, with an IC50 of around 35 μM. Research Area：Cancer Targets：Bcl-2 Family|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Anti-Cancer Compound Library;Anti-Blood Cancer Compound Library;Transcription Factor-Targeted Library; Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic […]