Master of Bioactive Molecules | Inhibitors, Screening Libraries & Proteins
For research use only. We do not sell to patients. WYC-209 CAS No. : 2131803-90-0 Biological Activity：WYC-209, a synthetic retinoid, is a retinoic acid receptor (RAR) agonist. WYC-209 induces apoptosis primarily via the caspase 3 pathway (IC50=0.19 μM for inmalignant murine melanoma TRCs), and has long-term effects with little toxicity. Research Area：Cancer Targets：Autophagy|RAR/RXR|Apoptosis Related Screening Libraries:Bioactive […]
For research use only. We do not sell to patients. Goserelin CAS No. : 65807-02-5 Biological Activity：Goserelin (ICI 118630), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer[2]. Research Area：Cancer|Endocrinology Targets：GnRH Receptor|Apoptosis Related Small Molecules:Physalin A;Bomedemstat […]
For research use only. We do not sell to patients. Piclidenoson CAS No. : 152918-18-8 Biological Activity：Piclidenoson (IB-MECA) is a first-in-class, orally active and selective A3 adenosine receptor (A3AR) agonist. Piclidenoson exhibits antiproliferative effect and induces apoptosis in different cancer cell types like melanoma, leukemia. Piclidenoson can be used for the research of autoimmune inflammatory […]
For research use only. We do not sell to patients. GW9508 CAS No. : 885101-89-3 Biological Activity：GW9508 is a potent and selective G protein-coupled receptors FFA1 (GPR40) and GPR120 agonist with pEC50s of 7.32 and 5.46, respectively. GW9508 shows ~100-fold selectivity for GPR40 over GPR120. GW9508 is inactive against other GPCRs, kinases, proteases, integrins and […]
For research use only. We do not sell to patients. CHPG sodium salt CAS No. : 1303993-73-8 Biological Activity：CHPG sodium salt is a selective mGluR5 agonist, and attenuates SO2-induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells. CHPG sodium salt protects against traumatic brain injury (TBI) in vitro and in vivo by […]