Tag: Activator

For research use only. We do not sell to patients. 3α-Hydroxymogrol CAS No. : 1343402-73-2 Biological Activity：3α-Hydroxymogrol is a triterpenoid isolated from Siraitia grosvenorii Swingle, acts as a potent AMPK activator, and enhances AMPK phosphorylation. Research Area：Metabolic Disease Targets：AMPK Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus; Related Small Molecules:AMPK activator 4;ZLN024;YLF-466D;BAY-3827;HTH-01-015;TMPA;AICAR;Cimiracemoside C;HL271;EB-3D;COH-SR4;AMPK activator […]

For research use only. We do not sell to patients. SRT 1720 Hydrochloride CAS No. : 2060259-60-9 Biological Activity：SRT 1720 Hydrochloride is a selective activator of SIRT1 with an EC50 of 0.10 μM, and shows less potent activities on SIRT2 and SIRT3. Research Area：Metabolic Disease Targets：Autophagy|Sirtuin Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound […]

For research use only. We do not sell to patients. L-Leucine-15N CAS No. : 59935-31-8 Biological Activity：L-Leucine-15N is the 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[2]. Research Area：Metabolic Disease Targets：mTOR|Endogenous Metabolite Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Nicotinamide N-oxide;3-Hydroxyglutaric acid-d5;DPPC-d62;SDMA-d6;2-Mercaptobenzothiazole;N-Acetyl-L-glutamic acid-d5;(3R,5S)-3-Hydroxy Cotinine-d3;Biliverdin hydrochloride;D-Glucose-13C,d1-3;2,3-Diaminopropionic acid hydrochloride;Docosanoic acid-d3;Choline-d6 chloride;Pregnenolone monosulfate […]

For research use only. We do not sell to patients. (S)-(+)-Modafinic acid-d5 Biological Activity：(S)-(+)-Modafinic acid-d5 is deuterium labeled (S)-(+)-Modafinic acid. Research Area：Neurological Disease Targets：Potassium Channel Related Small Molecules:Kv3 modulator 2;Brompheniramine-d6 maleate;Pinacidil;AMP-PNP tetralithium;IK1 inhibitor PA-6;VU590;Domiphen bromide;Mesoridazine benzenesulfonate;Tetrandrine;20(S)-Ginsenoside Rg3;Ketanserin;PE 22-28;Ifenprodil tartrate;Brompheniramine maleate;L-Palmitoylcarnitine-d3 hydrochloride;Phe-Met-Arg-Phe amide trifluoroacetate;Mitiglinide;Flupirtine-d4 hydrochloride;Kaliotoxin (1-37);Tifenazoxide;Agitoxin-2 TFA Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural […]

For research use only. We do not sell to patients. STING agonist-10 CAS No. : 2259308-69-3 Biological Activity：STING agonist-10 (Compound 91) is a potent small molecule cyclic urea activator of STING with the EC50 of 2600 nM. Activation of STING is a highly promising approach in immunotherapy. Research Area：Inflammation/Immunology|Cancer Targets：STING Related Small Molecules:STING agonist-3 trihydrochloride;BSP16;IACS-8803 […]

For research use only. We do not sell to patients. CDN-A CAS No. : 2586047-09-6 Biological Activity：CDN-A is a cyclic di-nucleotide, it can be used to synthesis antibody-drug conjugate (ADC). Cyclic di-nucleotides are potent stimulators of innate and adaptive immune responses. In humans, cyclic di-nucleotide, which are either produced endogenously in response to foreign DNA […]

For research use only. We do not sell to patients. Melittin CAS No. : 20449-79-0 Biological Activity：Melittin is a PLA2 activator, stimulates the activity of the low molecular weight PLA2, while it does not the increase activity of the high molecular weight PLA2[2]. Research Area：Cancer|Inflammation/Immunology Targets：Phospholipase Related Small Molecules:GK563;DPTIP;Cambinol;Neomycin sulfate;ONO-RS-082;ARN19874;LEI-401;ST271;Melittin TFA;(S)-Bromoenol lactone;GK187;D-Erythro-dihydrosphingosine-d7;FKGK11;PACOCF3;DL-erythro-Dihydrosphingosine;1-Naphthaleneacetic acid potassium salt;C12 […]

For research use only. We do not sell to patients. 7-Methoxyisoflavone CAS No. : 1621-56-3 Biological Activity：7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase (AMPK). Research Area：Metabolic Disease|Cancer Targets：AMPK Related Screening Libraries:Natural Product-like Compound Library;Bioactive Compound Library Plus;Epigenetics Compound Library; Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Antioxidant […]

For research use only. We do not sell to patients. Tacalcitol CAS No. : 57333-96-7 Biological Activity：Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium. IC50 value: Target: Tacalcitol modulates immunological and inflammatory processes. Tacalcitol induces nerve growth factor production in epidermal keratinocytes. Research Area：Metabolic Disease Targets：VD/VDR Related Screening Libraries:Drug Repurposing Compound […]

For research use only. We do not sell to patients. Trimetazidine dihydrochloride CAS No. : 13171-25-0 Biological Activity：Trimetazidine dihydrochloride is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine dihydrochloride is an effective antianginal agent and a cytoprotective drug, […]