Tag: Activator

For research use only. We do not sell to patients. Corynoxine hydrochloride Biological Activity：Corynoxine hydrochloride, a tetracyclic oxindole alkaloid, is isolated from the hooks of Uncaria macrophylla. Corynoxine hydrochloride is a natural autophagy enhancer that promotes the clearance of alpha-synuclein via Akt/mTOR pathway. Research Area：Cancer|Neurological Disease Targets：Autophagy Related Small Molecules:Physalin A;Stauprimide;Pregnenolone monosulfate sodium;Notoginsenoside Fc;AGN 193109-d7;AT9283;Ciclopirox-d11;BIX-01294;Wogonoside;Cyclovirobuxine […]

For research use only. We do not sell to patients. Kauran-16,17-diol CAS No. : 16836-31-0 Biological Activity：Kauran-16,17-diol (ent-Kauran-16β,17-diol), a natural diterpene, posseses anti-tumor and inducing-apoptosis activity, with a IC50 of 17 μM on inhibiting NO production in LPS-stimulated RAW 264.7 macrophages[2]. Research Area：Cancer|Inflammation/Immunology Targets：Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis […]

For research use only. We do not sell to patients. Chenodeoxycholic Acid-d9 Biological Activity：Chenodeoxycholic Acid-d9 (CDCA-d9) is the deuterium labeled Chenodeoxycholic Acid. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism. Research Area：Metabolic Disease|Cancer Targets：Autophagy|FXR|Endogenous Metabolite Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Nicotinamide N-oxide;3-Hydroxyglutaric acid-d5;DPPC-d62;SDMA-d6;2-Mercaptobenzothiazole;N-Acetyl-L-glutamic acid-d5;(3R,5S)-3-Hydroxy Cotinine-d3;Biliverdin hydrochloride;D-Glucose-13C,d1-3;2,3-Diaminopropionic acid […]

For research use only. We do not sell to patients. Methionine-d4 Biological Activity：Methionine-d4 is the deuterium labeled Methionine. Methionine (MRX-1024; D-Methionine) is an effective chemoprotective agent which can also inhibit the neuronal activity through GABAA receptor activation. Targets：GABA Receptor|Endogenous Metabolite Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Nicotinamide N-oxide;3-Hydroxyglutaric acid-d5;DPPC-d62;SKF89976A hydrochloride;SDMA-d6;2-Mercaptobenzothiazole;N-Acetyl-L-glutamic acid-d5;(3R,5S)-3-Hydroxy Cotinine-d3;Biliverdin hydrochloride;D-Glucose-13C,d1-3;2,3-Diaminopropionic acid hydrochloride;Docosanoic acid-d3;Choline-d6 chloride;Pregnenolone […]

For research use only. We do not sell to patients. Myosmine-d4 CAS No. : 66148-17-2 Biological Activity：Myosmine-d4 is the deuterium labeled Myosmine. Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM[2]. Research Area：Metabolic Disease Targets：nAChR Related Small Molecules:Spinosad;Pyrantel;NS 9283;Benzethonium […]

For research use only. We do not sell to patients. Calcium dobesilate CAS No. : 20123-80-2 Biological Activity：Calcium dobesilate, a vasoprotective, is widely used in chronic venous disease, diabetic retinopathy and the symptoms of haemorrhoidal attack in many countries. Research Area：Others Targets：Apoptosis Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive […]

For research use only. We do not sell to patients. 3-Deoxyaconitine CAS No. : 3175-95-9 Biological Activity：3-Deoxyaconitine a diterpenoid alkaloid, is a sodium channel activator. Research Area：Others Targets：Sodium Channel Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Natural Product Library;Macrocyclic Compound Library;Traditional Chinese Medicine Active Compound Library;Alkaloids Library;Plant-Sourced Natural Product Library; […]

For research use only. We do not sell to patients. NF-κΒ activator 2 CAS No. : 2375281-44-8 Biological Activity：NF-κΒ activator 2 is a potent and orally active NF-ҡB activator, with an EC50 of 1.58 μM. NF-κΒ activator 2 induces SOD2 through increasing NF-ҡB expression and activation. NF-κΒ activator 2 can be used for the research […]

For research use only. We do not sell to patients. ISX-9 CAS No. : 832115-62-5 Biological Activity：ISX-9 (Isoxazole 9) is a potent inducer of adult neural stem cell differentiation. ISX-9 activates Ca2+ influx through both voltage-gated Ca2+ channels and NMDA receptors and increases neuroD expression. ISX-9 also induces cardiomyogenic differentiation of Notch-activated epicardium-derived cells (NECs)[2][3]. […]

For research use only. We do not sell to patients. Licarin B CAS No. : 51020-87-2 Biological Activity：Licarin B, a nitric oxide production inhibitor extracted from the component of the seeds of Myristica fragrans, improves insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway[2][3]. Research Area：Metabolic Disease Targets：GLUT|PPAR Related Screening Libraries:Natural Product […]