epigenetics modulation frontier

Product Name : 10-AcetylphenothiazineSynonym: 10-Acetyl-10H-phenothiazine, 1-(10H-Phenothiazin-10-yl)ethanone, NSC 14724, J 3-55CAS : 1628-29-1Molecular formula:C14H11NOSMolecular Weight : 241.{{2797026-97-0} site|{2797026-97-0} Protocol|{2797026-97-0} In Vitro|{2797026-97-0} custom synthesis} 31Purity: ≥95% (NMR)Specifications: Purity ≥95% (NMR)|Appearance Beige powder|Identity 1H-NMR|PropertiesSolvents chloroform|{{6090-95-5} MedChemExpress|{6090-95-5} Protocol|{6090-95-5} In Vitro|{6090-95-5} custom synthesis} PMID:30571052 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference […]

Product Name : 4-Acetamido-5-nitrophthalic anhydrideSynonym: N-(1,3-Dihydro-6-nitro-1,3-dioxo-5-isobenzofuranyl)acetamide , N-(6-Nitro-1,3-dioxo-1,3-dihydroisobenzofuran-5-yl)acetamideCAS : 209324-72-1Molecular formula:C10H6N2O6Molecular Weight : 250.{{2229047-91-8} site|{2229047-91-8} Biological Activity|{2229047-91-8} Formula|{2229047-91-8} custom synthesis} 16Purity: ≥98% (GC)Specifications: Purity ≥98% (GC)|Appearance Yellow crystals|Identity 1H-NMR|PropertiesSolvents DMSO|Melting Point 177-179°C|DownloadsSafety Data Sheet CDX A0245 MSDS.{{4800-94-6} web|{4800-94-6} Biological Activity|{4800-94-6} Formula|{4800-94-6} supplier} pdf|PMID:29489283 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals […]

Product Name : TriacetylresveratrolDescription:Triacetylresveratrol, an acetylated analog of Resveratrol. Triacetylresveratrol decreases the phosphorylation of STAT3 and NF-κB in a dose- and time- dependent manner in PANC-1 and BxPC-3 cells. Anticancer effects.CAS: 42206-94-0Molecular Weight:354.35Formula: C20H18O6Chemical Name: 3-(acetyloxy)-5-[(E)-2-[4-(acetyloxy)phenyl]ethenyl]phenyl acetateSmiles : CC(=O)OC1=CC(=CC(=C1)OC(C)=O)/C=C/C1C=CC(=CC=1)OC(C)=OInChiKey: PDAYUJSOJIMKIS-SNAWJCMRSA-NInChi : InChI=1S/C20H18O6/c1-13(21)24-18-8-6-16(7-9-18)4-5-17-10-19(25-14(2)22)12-20(11-17)26-15(3)23/h4-12H,1-3H3/b5-4+Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature […]

Product Name : N-(3-Methoxybenzyl)PalmitamideDescription:N-(3-Methoxybenzyl)Palmitamide is a promising inhibitor of FAAH for the treatment of pain, inflammation and CNS degenerative disorders.CAS: 847361-96-0Molecular Weight:375.59Formula: C24H41NO2Chemical Name: N-[(3-methoxyphenyl)methyl]hexadecanamideSmiles : CCCCCCCCCCCCCCCC(=O)NCC1=CC(=CC=C1)OCInChiKey: FIQGQTITXPTKIY-UHFFFAOYSA-NInChi : InChI=1S/C24H41NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19-24(26)25-21-22-17-16-18-23(20-22)27-2/h16-18,20H,3-15,19,21H2,1-2H3,(H,25,26)Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of AnalysisStorage Condition : Dry, […]

Product Name : Adrenomedullin (AM) (1-52), humanDescription:Adrenomedullin (AM) (1-52), human is a 52-amino acid peptide, which affects cell proliferation and angiogenesis in cancer.CAS: 148498-78-6Molecular Weight:6028.73Formula: C264H406N80O77S3Chemical Name: (3S)-3-{[(1S)-1-{[(1S)-1-{[(2S)-1-[(2S)-2-{[(1S)-1-{[(1S)-1-{[(1S)-5-amino-1-{[(1S,2S)-1-{[(2S)-1-[(2S)-2-{[(1S)-3-carbamoyl-1-[({[(1S)-1-carbamoyl-2-(4-hydroxyphenyl)ethyl]carbamoyl}methyl)carbamoyl]propyl]carbamoyl}pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]carbamoyl}-2-methylbutyl]carbamoyl}pentyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-4-carbamimidamidobutyl]carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]carbamoyl}-2-methylpropyl]carbamoyl}-2-carbamoylethyl]carbamoyl}-3-[(2S)-6-amino-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-{[(4R,7S,13S,16S,19R)-19-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S,3S)-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]-5-carbamimidamidopentanamido]-4-carbamoylbutanamido]-3-hydroxypropanamido]-4-(methylsulfanyl)butanamido]-3-carbamoylpropanamido]-3-carbamoylpropanamido]-3-phenylpropanamido]-4-carbamoylbutanamido]acetamido}-3-methylpentanamido]-5-carbamimidamidopentanamido]-3-hydroxypropanamido]-3-phenylpropanamido]acetamido}-13-benzyl-16-(3-carbamimidamidopropyl)-7-[(1R)-1-hydroxyethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]formamido}-3-hydroxybutanamido]-3-methylbutanamido]-4-carbamoylbutanamido]hexanamido]-4-methylpentanamido]propanamido]-3-(1H-imidazol-5-yl)propanamido]-4-carbamoylbutanamido]-3-methylpentanamido]-3-(4-hydroxyphenyl)propanamido]-4-carbamoylbutanamido]-3-phenylpropanamido]-3-hydroxybutanamido]-3-carboxypropanamido]hexanamido]-3-carboxypropanamido]hexanamido]propanoic acidSmiles : CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CC1C=CC(O)=CC=1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)NCC(=O)N[C@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC2C=CC=CC=2)NC(=O)[C@H](CCCNC(N)=N)NC1=O)[C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1C=CC(O)=CC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC1C=CC(O)=CC=1)C(N)=OInChiKey: ULCUCJFASIJEOE-NPECTJMMSA-NInChi : InChI=1S/C264H406N80O77S3/c1-19-132(10)207(335-200(366)120-294-216(377)160(78-84-189(270)355)308-234(395)171(107-142-52-30-24-31-53-142)322-237(398)176(112-196(277)362)324-238(399)175(111-195(276)361)323-230(391)166(90-101-422-18)312-245(406)182(123-346)332-229(390)163(81-87-192(273)358)309-220(381)156(60-42-95-289-261(280)281)302-215(376)151(269)103-144-66-72-148(352)73-67-144)253(414)315-159(63-45-98-292-264(286)287)226(387)331-183(124-347)246(407)320-170(106-141-50-28-23-29-51-141)219(380)295-119-199(365)301-185-126-423-424-127-186(334-256(417)210(137(15)349)336-201(367)121-296-218(379)169(105-140-48-26-22-27-49-140)319-224(385)157(307-247(185)408)61-43-96-290-262(282)283)248(409)342-212(139(17)351)258(419)338-206(131(8)9)252(413)316-164(82-88-193(274)359)227(388)303-152(56-34-38-91-265)221(382)318-168(102-129(4)5)233(394)298-135(13)214(375)317-174(110-147-117-288-128-297-147)236(397)311-165(83-89-194(275)360)232(393)340-208(133(11)20-2)254(415)328-172(109-146-70-76-150(354)77-71-146)235(396)310-162(80-86-191(272)357)228(389)321-173(108-143-54-32-25-33-55-143)242(403)341-211(138(16)350)257(418)329-180(116-204(372)373)240(401)305-154(58-36-40-93-267)222(383)326-178(114-202(368)369)239(400)304-153(57-35-39-92-266)223(384)327-179(115-203(370)371)241(402)325-177(113-197(278)363)243(404)337-205(130(6)7)251(412)299-136(14)259(420)343-99-46-64-187(343)249(410)313-158(62-44-97-291-263(284)285)225(386)330-181(122-345)244(405)306-155(59-37-41-94-268)231(392)339-209(134(12)21-3)255(416)333-184(125-348)260(421)344-100-47-65-188(344)250(411)314-161(79-85-190(271)356)217(378)293-118-198(364)300-167(213(279)374)104-145-68-74-149(353)75-69-145/h22-33,48-55,66-77,117,128-139,151-188,205-212,345-354H,19-21,34-47,56-65,78-116,118-127,265-269H2,1-18H3,(H2,270,355)(H2,271,356)(H2,272,357)(H2,273,358)(H2,274,359)(H2,275,360)(H2,276,361)(H2,277,362)(H2,278,363)(H2,279,374)(H,288,297)(H,293,378)(H,294,377)(H,295,380)(H,296,379)(H,298,394)(H,299,412)(H,300,364)(H,301,365)(H,302,376)(H,303,388)(H,304,400)(H,305,401)(H,306,405)(H,307,408)(H,308,395)(H,309,381)(H,310,396)(H,311,397)(H,312,406)(H,313,410)(H,314,411)(H,315,414)(H,316,413)(H,317,375)(H,318,382)(H,319,385)(H,320,407)(H,321,389)(H,322,398)(H,323,391)(H,324,399)(H,325,402)(H,326,383)(H,327,384)(H,328,415)(H,329,418)(H,330,386)(H,331,387)(H,332,390)(H,333,416)(H,334,417)(H,335,366)(H,336,367)(H,337,404)(H,338,419)(H,339,392)(H,340,393)(H,341,403)(H,342,409)(H,368,369)(H,370,371)(H,372,373)(H4,280,281,289)(H4,282,283,290)(H4,284,285,291)(H4,286,287,292)/t132-,133-,134-,135-,136-,137+,138+,139+,151-,152-,153-,154-,155-,156-,157-,158-,159-,160-,161-,162-,163-,164-,165-,166-,167-,168-,169-,170-,171-,172-,173-,174-,175-,176-,177-,178-,179-,180-,181-,182-,183-,184-,185-,186-,187-,188-,205-,206-,207-,208-,209-,210-,211-,212-/m0/s1Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of […]

Product Name : O-Desisobutyl-O-n-propyl FebuxostatDescription:O-Desisobutyl-O-n-propyl Febuxostat, extracted from the patent CN 103467412, is an xanthine oxidase inhibitor.CAS: 1530308-87-2Molecular Weight:302.35Formula: C15H14N2O3SChemical Name: 2-(3-cyano-4-propoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acidSmiles : CC1N=C(SC=1C(O)=O)C1=CC(C#N)=C(C=C1)OCCCInChiKey: BWNYQPAKTQSUDL-UHFFFAOYSA-NInChi : InChI=1S/C15H14N2O3S/c1-3-6-20-12-5-4-10(7-11(12)8-16)14-17-9(2)13(21-14)15(18)19/h4-5,7H,3,6H2,1-2H3,(H,18,19)Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of AnalysisStorage Condition : Dry, dark and […]

Product Name : Hyocholic AcidCAS No.: 547-75-1Purity : 98.73%Shipping:Room temperature in the continental U.S. Other areas may vary.Storage : Powder: -20°C, 3 years; 4°C, 2 yearsIn solvent: -80°C, 6 months; -20°C, 1 monthSMILES: C[C@@H]([C@]1(CC[C@]2([C@@]3([C@@H]([C@@H]([C@@]4(C[C@@H](CC[C@@]4([C@]3(CC[C@@]21C)[H])C)O)[H])O)O)[H])[H])[H])CCC(O)=OProduct Description : Hyocholic Acid is a bile acid found in pig. Hyocholic Acid can also be found in urine samples from […]

Product Name : Anti-VEGFB(Reflocibart Biosimilar) AntibodyApplications: ELISA,Flow CytReactivity : Human VEGFBConjugate:UnconjugatedAdvantages : High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free productionDescription: | Description: Anti-VEGFB(Reflocibart Biosimilar) Antibody is a biosimilar antibody directed against Human VEGFB. | Isotype: Human IgG4 | Conjugate: Unconjugated | Specificity: Human VEGFB | Clonality: Monoclonal | Purity: Recombinant Expression and Affinity purified | […]

Product Name : UCB-9260Description:UCB-9260 is an orally active inhibitor that inhibits TNF signalling by stabilising an asymmetric form of the trimer. UCB-9260 binds TNF with Kd of 13 nM. UCB-9260 also inhibits NF-κB with IC50 of 202 nM after TNF stimulation.CAS: 1515888-53-5Molecular Weight:423.51Formula: C26H25N5OChemical Name: (1-(2, 5-dimethylbenzyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-benzo[d]imidazol-2-yl)(pyridin-4-yl)methanolSmiles : CN1C=C(C=N1)C1=CC2=C(C=C1)N=C(C(O)C1C=CN=CC=1)N2CC1=CC(C)=CC=C1CInChiKey: RZGFWGNCSYUEPR-UHFFFAOYSA-NInChi : InChI=1S/C26H25N5O/c1-17-4-5-18(2)21(12-17)16-31-24-13-20(22-14-28-30(3)15-22)6-7-23(24)29-26(31)25(32)19-8-10-27-11-9-19/h4-15,25,32H,16H2,1-3H3Purity: ≥98% (or refer to […]

Product Name : Anti-KIT/CD117(Barzolvolimab Biosimilar) AntibodyApplications: ELISA,Flow CytReactivity : Human KIT/CD117Conjugate:UnconjugatedAdvantages : High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free productionDescription: | Description: Anti-KIT/CD117(Barzolvolimab Biosimilar) Antibody is a biosimilar antibody directed against Human KIT/CD117. | Isotype: Human IgG1 | Conjugate: Unconjugated | Specificity: Human KIT/CD117 | Clonality: Monoclonal | Purity: Recombinant Expression and Affinity purified | […]