Reference compound - epigenetics modulation frontier

MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin

Posted on December 20, 2022 by haoyuan2014

For research use only. We do not sell to patients. MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin CAS No. : 2414594-29-7 Biological Activity：MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (compound 21a), a camptothecin payload, can be conjugated to a monoclonal antibody (mAb) for the synthesis of camptothecin antibody-drug conjugate (ADC). 研究领域：Cancer Targets：ADC Cytotoxin Related Small Molecules:Sandramycin;(R)-Camptothecin-d5;Dolastatin 10;INX-SM-56;DC10SMe;Rebeccamycin;Duocarmycin TM;Fmoc-MMAE;Taltobulin;N-Me-L-Ala-maytansinol;CC-885-CH2-PEG1-NH-CH3;Camptothecin;Maytansinol;Tomaymycin DM;Hemiasterlin derivative-1;SGD-1882;Corixetan;Duostatin 5;PROTAC BRD4 Degrader-13;Dxd-d5;Tubulysin IM-1;Duocarmycin SA;Ansamitocin […]

TRPM8 antagonist 2

Posted on December 20, 2022 by haoyuan2014

For research use only. We do not sell to patients. TRPM8 antagonist 2 CAS No. : 259674-19-6 Biological Activity：TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist, with an IC50 of 0.2 nM, used in the research of neuropathic pain syndromes. 研究领域：Neurological Disease Targets：TRP Channel Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound […]

PSNCBAM-1

Posted on December 19, 2022December 20, 2022 by haoyuan2014

For research use only. We do not sell to patients. PSNCBAM-1 CAS No. : 877202-74-9 Biological Activity：PSNCBAM-1 is a selective CB1 receptor allosteric antagonist with an EC50 of 0.1 μM. PSNCBAM-1 can be used in the researches of obesity. Research Area：Metabolic Disease Targets：Cannabinoid Receptor Related Small Molecules:Pregnenolone monosulfate sodium;GW842166X;RVD-Hpα TFA;β-Caryophyllene;Hemopressin(rat) TFA;AM8936;Taranabant;Bay 59-3074;NESS 0327;CB1-IN-2;Olivetol;CB1/2 agonist 1;N-Oleoyl […]