Master of Bioactive Molecules | Inhibitors, Screening Libraries & Proteins
For research use only. We do not sell to patients. Bicalutamide CAS No. : 90357-06-5 Biological Activity：Bicalutamide is an orally active non-steroidal androgen receptor (AR) antagonist. Bicalutamide can be used for the research of prostate cancer. Research Area：Cancer Targets：Androgen Receptor|Autophagy Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library […]
For research use only. We do not sell to patients. HA130 CAS No. : 1229652-21-4 Biological Activity：HA130 is a selective autotaxin (ATX) inhibitor with an IC50 of 28 nM. Research Area：Cancer Targets：Phosphodiesterase (PDE) Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Covalent Screening Library;Anti-Alzheimer’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Colorectal Cancer […]
For research use only. We do not sell to patients. PROTAC CDK9 ligand-1 CAS No. : 2411021-95-7 Biological Activity：PROTAC CDK9 ligand-1 is a CDK9 ligand that can be used in the synthesis of PROTACs. Research Area：Cancer Targets：Ligands for Target Protein for PROTAC Related Small Molecules:BI-4464;PROTAC BRD4 ligand-2;PROTAC BRD9-binding moiety 1 hydrochloride;PROTAC IRAK4 ligand-1;Apcin-A;Ipatasertib-NH2 dihydrochloride;SirReal1-O-propargyl;PD0325901-O-C2-dioxolane;CDK9-IN-10;TSPO ligand-1;SLF […]
For research use only. We do not sell to patients. BTK-IN-14 CAS No. : 2764674-60-2 Biological Activity：BTK-IN-14 is a potent inhibitor of BTK. BTK plays an important role in signaling mediated by B cell antigen receptor (BCR) and Fcγreceptor (FcγR) in B cells and myeloid cells, respectively. BTK-IN-14 has the potential for the research of […]
For research use only. We do not sell to patients. Antioxidant agent-2 CAS No. : 2250106-92-2 Biological Activity：Antioxidant agent-2 (comp 3c), an BBB-penetrated antioxidant agent and a selective metal ions chelator, presents good neuroprotective effect and hepatoprotective effect for the study of Alzheimer’s disease. Research Area：Neurological Disease Targets：Amyloid-β Related Small Molecules:β-Amyloid (13-27);Saikosaponin C;β-Amyloid (1-42), (rat/mouse) […]
For research use only. We do not sell to patients. UPF-523 CAS No. : 168560-79-0 Biological Activity：UPF-523 (AIDA), a rigid (carboxyphenyl) glycine derivative, is a relatively potent and selective antagonist of group I metabotropic glutamate receptors (mGlu1a) with an IC50 of 214 μM. But UPF-523 has no effect on group II (mGlu2), group III (mGlu4) […]
For research use only. We do not sell to patients. Sodium stibogluconate CAS No. : 16037-91-5 Biological Activity：Sodium stibogluconate (Stibogluconate trisodium nonahydrate) is a potent inhibitor of protein tyrosine phosphatase. Sodium stibogluconate inhibits 99% of SHP-1, SHP-2 and PTP1B activity at 10, 100, 100 μg/mL, respectively. Research Area：Cancer Targets：Parasite|SHP2|Phosphatase Related Screening Libraries:Drug Repurposing Compound Library […]
For research use only. We do not sell to patients. PI3Kα-IN-6 CAS No. : 2272894-14-9 Biological Activity：PI3Kα-IN-6 (Compound 5b) is a PI3Kα inhibitor. PI3Kα-IN-6 exhibits anticancer potential and no toxicity in normal cells. PI3Kα-IN-6 increases generation of ROS, reduces mitochondrial membrane potential (MMP) and induces apoptosis. Research Area：Cancer Targets：Reactive Oxygen Species|Apoptosis|PI3K Related Small Molecules:D-α-Hydroxyglutaric acid […]
For research use only. We do not sell to patients. ML141 CAS No. : 71203-35-5 Biological Activity：ML141 (CID-2950007) is a potent, allosteric, selective and reversible non-competitive inhibitor of Cdc42 GTPase. ML141 inhibits Cdc42 wild type and Cdc42 Q61L mutant with EC50s of 2.1 and 2.6 μM, respectively. ML141 shows low micromolar potency and selectivity against […]
For research use only. We do not sell to patients. Atrasentan CAS No. : 173937-91-2 Biological Activity：Atrasentan (ABT-627) is an endothelin receptor antagonist with IC50 of 0.0551 nM for ETA. 研究领域：Cancer|Endocrinology|Cardiovascular Disease Targets：Endothelin Receptor Related Small Molecules:BQ-788;[Asn18] Endothelin-1, human;Endothelin-3, human, mouse, rabbit, rat TFA;IRL 2500;Sarafotoxin S6c;Sarafotoxin S6a;ANP (1-30), frog;IRL-1620 TFA;Tezosentan;ACT-373898;Ro 46-2005;Ro 46-8443;[Ala2] Endothelin-3, human;ZD-1611;PD-159020;Aminaftone;Aprocitentan-d4;Endothelin 1 […]