Master of Bioactive Molecules | Inhibitors, Screening Libraries & Proteins
For research use only. We do not sell to patients. BI-2081 CAS No. : 1458656-71-7 Biological Activity：BI-2081 is a GPR40 (FFAR1) partial agonist (EC50: 4 nM). BI-2081 induces glucose depending insulin secretion and reduces the plasma glucose concentration. BI-2081 can be used in the research of metabolic diseases, in particular diabetes type 2. Research Area：Metabolic […]
For research use only. We do not sell to patients. Methyl aminolevulinate CAS No. : 33320-16-0 Biological Activity：Methyl aminolevulinate is an agent used as a sensitizer in photodynamic therapy (PDT). Methyl aminolevulinate is a prodrug that can be metabolized to Protoporphyrin IX. Research Area：Cancer|Inflammation/Immunology Targets：Reactive Oxygen Species Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Chitoheptaose heptahydrochloride;N-Acetyl-D-cysteine;Topoisomerase I/II inhibitor […]
For research use only. We do not sell to patients. E7090 CAS No. : 1622204-21-0 Biological Activity：E7090 is an orally available, potent, and selective FGFR inhibitor with IC50s of 0.71 nM, 0.50 nM, 1.2 nM, and 120 nM for FGFR1/FGFR2/FGFR3/FGFR4, respectively. Research Area：Cancer Targets：FGFR Related Small Molecules:Ferulic acid-13C3;FGFR-IN-7;PP58;FGFR3-IN-1;ENMD-2076 Tartrate;R1530;FGFR3-IN-3;Tyrosine kinase-IN-1;Heparan Sulfate;Futibatinib;SU4984;Roblitinib;PD173074;PF 477736;FGFR4-IN-8;Lucitanib;Masitinib;Zoligratinib;FGFR4-IN-4;BLU9931;SM1-71;VSPPLTLGQLLS TFA;TG 100801;FGFR1 inhibitor-6 […]
“ For research use only. We do not sell to patients. (+)-Tetrabenazine CAS No. : 1026016-83-0 Biological Activity：(+)-Tetrabenazine ((+)-TBZ; (3R,11bR)-TBZ; (3R,11bR)-Tetrabenazine) is a reversible inhibitor of vesicular monoamine transporter 2 (VMAT-2), inhibits transport by VMAT2 with 10-fold greater potency than transport by VMAT1. target: VMAT-2 In vitro: (+)-Tetrabenazine inhibit the activity of the transporter but […]
For research use only. We do not sell to patients. ABL127 CAS No. : 1073529-41-5 Biological Activity：ABL127 is a selective and covalent inhibitor of protein methylesterase 1 (PME-1) with IC50s of 6.4 nM and 4.2 nM in HEK293T and MDA-MB-231 cells, respectively. Research Area：Cancer Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide […]
For research use only. We do not sell to patients. FAAH/MAGL-IN-3 Biological Activity：FAAH/MAGL-IN-3 (Compound 10) is an irreversible fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) dual inhibitor with IC50 values of 179 and 759 nM against FAAH and MAGL, respectively. FAAH/MAGL-IN-3 shows low PAMPA (Parallel Artificial Membrane Permeability Assay) permeability. Research Area：Neurological Disease […]
“ For research use only. We do not sell to patients. Meclofenoxate hydrochloride CAS No. : 3685-84-5 Biological Activity：Meclofenoxate hydrochloride, an ester of dimethylethanolamine (DMAE) and 4-chlorophenoxyacetic acid (pCPA), has been shown to improve memory, have a mentally stimulating effect, and improve general cognition. IC50 value: Target: nootropic Meclofenoxate, administered in a dose of 50 […]
For research use only. We do not sell to patients. Antibacterial agent 111 CAS No. : 2448358-84-5 Biological Activity：Antibacterial agent 111 (Compound 3) is an antibacterial agent with MIC values of 3.90 μg/mL and 0.49 μg/mL against B. cereus and K. pneumonia, respectively. Antibacterial agent 111 firmly binds with tyrosyl-tRNA synthetase residues. Research Area：Infection Targets：Bacterial […]
For research use only. We do not sell to patients. DprE1-IN-1 CAS No. : 920459-41-2 Biological Activity：DprE1-IN-1 is a potent, orally active DprE1 inhibitor with favorable hepatocyte stability, low cytotoxicity and low hERG channel inhibition. DprE1-IN-1 displays potent activity against both drug-susceptible and clinically isolated drug-resistant Tuberculosis strains with MICs
For research use only. We do not sell to patients. WIN 55,212-2 Mesylate CAS No. : 131543-23-2 Biological Activity：WIN 55,212-2 Mesylate is a potent aminoalkylindole cannabinoid (CB) receptor agonist with Kis of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively. Research Area：Neurological Disease Targets：Cannabinoid Receptor Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G […]