Master of Bioactive Molecules | Inhibitors, Screening Libraries & Proteins
For research use only. We do not sell to patients. DCEBIO CAS No. : 60563-36-2 Biological Activity：DCEBIO, a derivative of 1-EBIO, is an extremely potent activator of Cl– secretion in T84 colonic cells. DCEBIO stimulates Cl– secretion via the activation of hIK1 K+ channels and the activation of an apical membrane Cl– conductance[2]. Research Area：Inflammation/Immunology […]
For research use only. We do not sell to patients. EGFR/CSC-IN-1 Biological Activity：EGFR/CSC-IN-1 is a potential EGFR (IC50 10.52 nM) and cancer stem cell (CSC) dual inhibitor for triple-negative breast cancer treatment. Research Area：Cancer Targets：EGFR Related Small Molecules:NSC81111;pp60 (v-SRC) Autophosphorylation Site, Phosphorylated;BMS-690514;Osimertinib-13C,d3;EGFR-IN-5;FGFR2-IN-3;Genistein;Epertinib hydrochloride;UNC-CA359;Osimertinib mesylate;AV-412 free base;Nelipepimut-S;Falnidamol;HER2-IN-6;PROTAC EGFR degrader 7;CHMFL-EGFR-202;Avitinib;Naquotinib;Lavendustin A;EAI001;EGFR/HER2/CDK9-IN-2;Cyasterone;DP-C-4;Allitinib Trending products：Recombinant Proteins | Bioactive […]
For research use only. We do not sell to patients. AE-3763 CAS No. : 291778-77-3 Biological Activity：AE-3763 is a peptide-based human neutrophil elastase inhibitor with an IC50 of 29 nM. Research Area：Inflammation/Immunology|Cardiovascular Disease Targets：Elastase Related Screening Libraries:Bioactive Compound Library Plus; Related Small Molecules:Cyclotheonellazole A;JCP174;BAY-678 racemate;Elastase-IN-1;19α-Hydroxyasiatic acid;Tutuilamide A;MDL 101146;Lodelaben;GW311616 hydrochloride;Elastatinal;DMP 777;BAY-85-8501;FK706;SSR69071;Elastase from porcine pancreas;Secologanoside;Tyrosinase/elastase-IN-1;ZD8321;ZD-0892 Trending products：Recombinant […]
For research use only. We do not sell to patients. Cantrixil CAS No. : 2135511-22-5 Biological Activity：Cantrixil (TRX-E-002-1), an active enantiomer of TRX-E-002, is a second-generation super-benzopyran (SBP) compound. Cantrixil increases phosphorylated c-Jun levels resulting in caspase-mediated apoptosis in ovarian cancer cells. Cantrixil has potent pan anti-cancer activity against a broad range of cancer phenotypes[2]. […]
For research use only. We do not sell to patients. Fosmidomycin sodium salt CAS No. : 66508-37-0 Biological Activity：Fosmidomycin sodium salt is a phosphonic acid antibiotic and a antimalarial drug, which is active against both Gram-negative and Gram-positive bacteria. Research Area：Infection Targets：Bacterial|Antibiotic Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Anti-Infection […]
For research use only. We do not sell to patients. (S)-Purvalanol B Biological Activity：(S)-Purvalanol B is the S enantiomer of Purvalanol B. Purvalanol B is a cyclin-dependent kinase inhibitor. Research Area：Others Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide (323-339);((3-Fluorophenyl)sulfonyl)glycine;7ß-Hydroxycholesterol-d7;MALAT1-IN-1;Sibiricose A1;Mefruside-d3;Ethacrynic acid mercapturate-d3;FLAG peptide;Neocurdione Trending products：Recombinant Proteins | Bioactive Screening Libraries | […]
For research use only. We do not sell to patients. 3CPLro-IN-1 CAS No. : 2432956-06-2 Biological Activity：3CPLro-IN-1 (compound A17) is a potent and orally active inhibitor of SARS-CoV-2 3CLpro with an IC50 of 5.65 μM. 3-Chymotrypsin-like cysteine protease (3CLpro) is an indispensable protein in viral replication and represents an attractive drug target for fighting COVID-19. […]
For research use only. We do not sell to patients. Dyrk1A/B-IN-1 Biological Activity：Dyrk1A/B-IN-1 (compound 3n) is a potent, selective and cell-permeable DYRK1A and DYRK1B inhibitor with Kis of 67.8 nM and 237.9 nM, and IC50s of 1.1 μM and 0.8 μM, respectively. Dyrk1A/B-IN-1 is not toxic to human cells. Dyrk1A/B-IN-1 can be used for researching […]
For research use only. We do not sell to patients. RI-962 CAS No. : 2763831-53-2 Biological Activity：RI-962 is a potent and selective receptor-interacting protein kinase 1 (RIPK1) inhibitor. RI-962 inhibits RIPK1 with an IC50 value of 35.0 nM. RI-962 can be used for the research of nervous system diseases and inflammatory diseases. Research Area：Inflammation/Immunology|Neurological Disease Targets：Necroptosis|RIP […]
For research use only. We do not sell to patients. LeuRS-IN-1 hydrochloride CAS No. : 1364683-67-9 Biological Activity：LeuRS-IN-1 hydrochloride is a potent, orally active M. tuberculosis leucyl-tRNA synthetase (M.tb LeuRS) inhibitor. LeuRS-IN-1 hydrochloride has IC50 and Kd values of 0.06 μM, 0.075 μM for M.tb LeuRS, respectively. LeuRS-IN-1 hydrochloride inhibits human cytoplasmic LeuRS (IC50=38.8 μM), […]