Inhibitory Antibodies - epigenetics modulation frontier

Nemonoxacin

Posted on March 20, 2025March 20, 2025 by haoyuan2014

Description：Nemonoxacin (TG-873870) is an orally active and potent broad-spectrum antibiotic. Nemonoxacin shows good inhibitory activity against different species of staphylococci, streptococci, and enterococci, Neisseria gonorrhoeae, and Haemophilus influenza. Nemonoxacin can be used in the study of bacterial infections and community-acquired pneumonia[1][2][3]. IC50 & Target：Bacterial[1][2][3]. In Vitro：Nemonoxacin (0–5.51 µM; 24 h) shows good antibacterial activity in vitro[1]. MedChemExpress (MCE) has not independently confirmed the […]

GJ103 and Lamin B1 Antibody: How to Conduct Chronic Kidney Disease Research?

Posted on March 19, 2025March 19, 2025 by haoyuan2014

Chronic kidney disease (CKD) poses a significant global health issue, leading to the progressive loss of kidney function. Renal fibrosis commonly accompanies CKD, characterized by excessive deposition of extracellular matrix (ECM). This process causes tissue remodeling and scarring in the renal parenchyma. Myofibroblasts drive renal fibrosis through their proliferation and activation. 1. Role of Meis1 in CKD […]

Tinurilimab

Posted on December 23, 2022 by haoyuan2014

For research use only. We do not sell to patients. Tinurilimab CAS No. : 2226224-30-0 Biological Activity：Tinurilimab (Bay 1834942) is an anti-CEACAM6 monoclonal antibody. CEACAM6 is an immune checkpoint regulator suppressing the activity of effector T-cells against tumors. Research Area：Cancer|Inflammation/Immunology Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide (323-339);((3-Fluorophenyl)sulfonyl)glycine;7ß-Hydroxycholesterol-d7;MALAT1-IN-1;Sibiricose A1;Mefruside-d3;Ethacrynic acid mercapturate-d3;FLAG […]