Product Name :
Methyltetrazine-PEG5-triethoxysilane
Description:
Methyltetrazine-PEG5-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
2353410-01-0
Molecular Weight:
639.81
Formula:
C29H49N5O9Si
Chemical Name:
1-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-N-[3-(triethoxysilyl)propyl]-3,6,9,12-tetraoxapentadecan-15-amide
Smiles :
CC1N=NC(=NN=1)C1=CC=C(C=C1)OCCOCCOCCOCCOCCC(=O)NCCC[Si](OCC)(OCC)OCC
InChiKey:
KTMPHUUZMIOJLF-UHFFFAOYSA-N
InChi :
InChI=1S/C29H49N5O9Si/c1-5-41-44(42-6-2,43-7-3)24-8-14-30-28(35)13-15-36-16-17-37-18-19-38-20-21-39-22-23-40-27-11-9-26(10-12-27)29-33-31-25(4)32-34-29/h9-12H,5-8,13-24H2,1-4H3,(H,30,35)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{SKF 81297} site|{SKF 81297} Neuronal Signaling|{SKF 81297} NF-κB|{SKF 81297} Technical Information|{SKF 81297} In Vivo|{SKF 81297} manufacturer}
Shelf Life:
≥12 months if stored properly.{{Roxadustat} web|{Roxadustat} Apoptosis|{Roxadustat} Technical Information|{Roxadustat} In Vitro|{Roxadustat} manufacturer|{Roxadustat} Epigenetics}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23415682
Additional information:
Methyltetrazine-PEG5-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 2353410-01-0|Molecular Weight: 639.81|Formula: C29H49N5O9Si|Chemical Name: 1-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-N-[3-(triethoxysilyl)propyl]-3,6,9,12-tetraoxapentadecan-15-amide|Smiles: CC1N=NC(=NN=1)C1=CC=C(C=C1)OCCOCCOCCOCCOCCC(=O)NCCC[Si](OCC)(OCC)OCC|InChiKey: KTMPHUUZMIOJLF-UHFFFAOYSA-N|InChi: InChI=1S/C29H49N5O9Si/c1-5-41-44(42-6-2,43-7-3)24-8-14-30-28(35)13-15-36-16-17-37-18-19-38-20-21-39-22-23-40-27-11-9-26(10-12-27)29-33-31-25(4)32-34-29/h9-12H,5-8,13-24H2,1-4H3,(H,30,35)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|