Product Name :
GV-196771A
Description:
GV-196771A is the sodium salt form of GV196771, is an NMDA receptor antagonist.
CAS:
166974-23-8
Molecular Weight:
423.22
Formula:
C20H13Cl2N2NaO3
Chemical Name:
sodium 4,6-dichloro-3-{[(3E)-2-oxo-1-phenylpyrrolidin-3-ylidene]methyl}-1H-indole-2-carboxylate
Smiles :
[Na+].[O-]C(=O)C1NC2C=C(Cl)C=C(Cl)C=2C=1/C=C1\CCN(C2C=CC=CC=2)C\1=O
InChiKey:
QHGFBRVHKFAYAP-YGCVIUNWSA-M
InChi :
InChI=1S/C20H14Cl2N2O3.Na/c21-12-9-15(22)17-14(18(20(26)27)23-16(17)10-12)8-11-6-7-24(19(11)25)13-4-2-1-3-5-13;/h1-5,8-10,23H,6-7H2,(H,26,27);/q;+1/p-1/b11-8+;
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{BTX-A51} web|{BTX-A51} Inducer|{BTX-A51} Activator|{BTX-A51} Technical Information|{BTX-A51} Data Sheet|{BTX-A51} supplier}
Shelf Life:
≥12 months if stored properly.{{Solithromycin} site|{Solithromycin} Antibiotic|{Solithromycin} Protocol|{Solithromycin} In stock|{Solithromycin} custom synthesis|{Solithromycin} Cancer}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:26446225
Additional information:
GV-196771A is the sodium salt form of GV196771, is an NMDA receptor antagonist.|Product information|CAS Number: 166974-23-8|Molecular Weight: 423.22|Formula: C20H13Cl2N2NaO3|Chemical Name: sodium 4,6-dichloro-3-{[(3E)-2-oxo-1-phenylpyrrolidin-3-ylidene]methyl}-1H-indole-2-carboxylate|Smiles: [Na+].[O-]C(=O)C1NC2C=C(Cl)C=C(Cl)C=2C=1/C=C1\CCN(C2C=CC=CC=2)C\1=O|InChiKey: QHGFBRVHKFAYAP-YGCVIUNWSA-M|InChi: InChI=1S/C20H14Cl2N2O3.Na/c21-12-9-15(22)17-14(18(20(26)27)23-16(17)10-12)8-11-6-7-24(19(11)25)13-4-2-1-3-5-13;/h1-5,8-10,23H,6-7H2,(H,26,27);/q;+1/p-1/b11-8+;|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|GV196771 is a potent antagonist of the modulatory glycine site of the N-methyl-D-aspartate receptor. GV196771 is a potent antagonist of the modulatory glycine site of the NMDA receptor developed for treatment of neuropathic pain. GV196771 is an NMDA receptor antagonist with low oral bioavailability in rats and mice. GV196771 has low oral bioavailability (Products are for research use only. Not for human use.|