Product Name :
CITED1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
ABCC1 antibody AI316840 antibody AU019144 antibody Cbp/p300-interacting transactivator 1 antibody Cbp/p300-interacting transactivator with GLU/ASP-rich C-terminal domain 1 antibody Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 antibody CITE1_HUMAN antibody CITED1 antibody melanocyte specific gene 1 antibody 展开
Function :
Transcriptional coactivator of the p300/CBP-mediated trancription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling; stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300.{{Belantamab} web|{Belantamab} Antibody-drug Conjugate/ADC Related|{Belantamab} Protocol|{Belantamab} References|{Belantamab} supplier|{Belantamab} Autophagy} Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human CITED1/ABCC1 121-193/193
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.{{4-Methylumbelliferyl} web|{4-Methylumbelliferyl} Metabolic Enzyme/Protease|{4-Methylumbelliferyl} Protocol|{4-Methylumbelliferyl} Data Sheet|{4-Methylumbelliferyl} supplier|{4-Methylumbelliferyl} Cancer} Avoid repeated freeze/thaw cycles.PMID:24220671 The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
20 KDa
Positive control :
Expressed only in melanocytes and testis.