Product Name :
CIDEC Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
Cell death activator antibody Cell death activator CIDE-3 antibody Cell death inducing DFFA like effector C antibody Cell death inducing DFFA like effector protein C antibody Cell death-inducing DFFA-like effector protein C antibody CIDE 3 antibody CIDE C antibody CIDE3 antibody CIDEC antibody CIDEC_HUMAN antibody 展开
Function :
May act as a CEBPB coactivator in white adipose tissueto control the expression of a subset of CEBPB downstream targetgenes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH (Bysimilarity). Binds to lipid droplets and regulates theirenlargement, thereby restricting lipolysis and favoring storage. Atfocal contact sites between lipid droplets, promotes directionalnet neutral lipid transfer from the smaller to larger lipiddroplets. The transfer direction may be driven by the internalpressure difference between the contacting lipid droplet pair. Whenoverexpressed in preadipocytes, induces apoptosis or increases cellsusceptibility to apoptosis induced by serum deprivation or TGFBtreatment. As mature adipocytes, that express high CIDEC levels,are quite resistant to apoptotic stimuli, the physiologicalsignificance of its role in apoptosis is unclear.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human CIDEC 101-200/238
Species reactivity:
Human, Mouse, Rat, Pig
Verify application:
WB, ELISA, IHC-P, FC, IF
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.{{Eribulin} web|{Eribulin} Apoptosis|{Eribulin} Biological Activity|{Eribulin} Description|{Eribulin} manufacturer|{Eribulin} Autophagy} Avoid repeated freeze/thaw cycles.{{Isocarboxazid} medchemexpress|{Isocarboxazid} Neuronal Signaling|{Isocarboxazid} Biological Activity|{Isocarboxazid} In stock|{Isocarboxazid} supplier|{Isocarboxazid} Autophagy} The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃.PMID:23453497 When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
27 KDa
Positive control :
Expressed mainly in adipose tissue, smallintestine, heart, colon and stomach and, at lower levels, in brain,kidney and liver.