Product Name :
CFLAR Mouse Monoclonal Antibody [D12-A3]
Predicted band size :
Observed band size :
Synonyms:
c-FLIP antibody CASH antibody CASP8 and FADD-like apoptosis regulator subunit p12 antibody Caspase homolog antibody Caspase-eight-related protein antibody Caspase-like apoptosis regulatory protein antibody Casper antibody Cellular FLICE-like inhibitory protein antibody Cflar antibody CFLAR_HUMAN antibody 展开
Function :
FLIP (FLICE inhibitory protein) is expressed as both long and short forms and is involved in the regulation of apoptosis. The short form of FLIP contains two death effector domains homologous to the death effector domain of the FAS-associating protein FADD. The long form of FLIP, which shares significant homology with the cysteine protease FLICE, contains an additional caspase-like domain, but lacks a catalytic active site and lacks the residues that form the substrate binding pocket in most caspases. FLIP has been designated by independent groups as Casper, I-FLICE, CLARP, FLAME-1 and MRIT. Although its exact role is still being elucidated, FLIP appears to be an important factor in the regulation of apoptosis downstream of all known death receptors.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Recombinant protein
Species reactivity:
Human, Mouse
Verify application:
WB, IHC-P, FC
Coupling :
unconjugated
Clone number:
D12-A3
RRID:
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
4℃; -20℃ for long term storage.{{Dodecyltrimethylammonium} web|{Dodecyltrimethylammonium} {Biochemical Assay Reagents}|{Dodecyltrimethylammonium} Purity & Documentation|{Dodecyltrimethylammonium} Purity|{Dodecyltrimethylammonium} supplier|{Dodecyltrimethylammonium} Epigenetics}
Storage buffer solution:
Purified antibody in PBS with 0.{{Tofacitinib} site|{Tofacitinib} JAK|{Tofacitinib} Protocol|{Tofacitinib} In stock|{Tofacitinib} supplier|{Tofacitinib} Epigenetics} 05% sodium azide.PMID:24211511
Subtype:
IgG1
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Positive control :
Human CFLAR recombinant protein, CFLAR-hIgGFc transfected HEK293 cell lysate, Jurkat, 3T3L1, Raji cell lysate, human cervical cancer tissue, human esophagus cancer tissue, Jurkat.