CENPC Recombinant Rabbit Monoclonal Antibody [JG36-15]

Function :
A replicated chromosome includes two kinetochores that control chromosome segregation during mitosis. The evolutionarily conserved Centromere Protein-C, CENP-C, is a kinetochore assembly protein.{{Cinacalcet} site|{Cinacalcet} GPCR/G Protein|{Cinacalcet} Protocol|{Cinacalcet} In Vitro|{Cinacalcet} custom synthesis|{Cinacalcet} Epigenetic Reader Domain} CENP-C is located on the fibers of the kinetochore and constitutes a kinetochore organizing center that tightly associates with DNA. CENP-C is necessary for the formation of a functional centromere, which indicates that CENP-C is important for mitotic progression. In addition, CENP-C is lost from centromeres during herpes simplex virus 1 infection, causing substantial structural changes in the kinetochore, which suggests that the structure of CENP-C is regulated during the cell cycle.{{Chloramphenicol} site|{Chloramphenicol} Autophagy|{Chloramphenicol} Purity & Documentation|{Chloramphenicol} In Vitro|{Chloramphenicol} supplier|{Chloramphenicol} Cancer}