Product Name :
CEACAM6 Mouse Monoclonal Antibody [A1E3]
Predicted band size :
Observed band size :
Synonyms:
Carcinoembryonic antigen related cell adhesion molecule 6 antibody Carcinoembryonic antigen related cell adhesion molecule 6 (non specific cross reacting antigen) antibody Carcinoembryonic antigen-related cell adhesion molecule 6 antibody CD 66c antibody CD66c antibody CD66c antigen antibody CEA LIKE PROTEIN antibody CEACAM 6 antibody CEACAM6 antibody CEAL antibody 展开
Function :
Cell surface glycoprotein that plays a role in cell adhesion and tumor progression. Intercellular adhesion occurs in a calcium- and fibronectin-independent manner. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. Plays a role in neutrophil adhesion to cytokine-activated endothelial cells. Plays a role as an oncogene by promoting tumor progression; positively regulates cell migration, cell adhesion to endothelial cells and cell invasion. Also involved in the metastatic cascade process by inducing gain resistance to anoikis of pancreatic adenocarcinoma and colorectal carcinoma cells.
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Recombinant protein within human CEACAM6 aa 1-150.
Species reactivity:
Human
Verify application:
IF-Cell, IHC-P, FC
Coupling :
unconjugated
Clone number:
A1E3
RRID:
AB_3068914
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
Store at +4℃ after thawing.{{Esaxerenone} site|{Esaxerenone} Vitamin D Related/Nuclear Receptor|{Esaxerenone} Biological Activity|{Esaxerenone} In Vivo|{Esaxerenone} supplier|{Esaxerenone} Cancer} Aliquot store at -20℃.{{Cefiderocol} MedChemExpress|{Cefiderocol} Anti-infection|{Cefiderocol} Protocol|{Cefiderocol} References|{Cefiderocol} custom synthesis|{Cefiderocol} Epigenetic Reader Domain} Avoid repeated freeze / thaw cycles.PMID:36014399
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG2a
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 37 kDa
Positive control :
HT-29, human lung tissue, human colon tissue, human colon carcinoma tissue, SW620.