Product Name :
CDk1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
Cdc 2 antibody Cdc2 antibody CDC28A antibody CDK 1 antibody CDK1 antibody CDK1_HUMAN antibody CDKN1 antibody CELL CYCLE CONTROLLER CDC2 antibody Cell division control protein 2 antibody Cell division control protein 2 homolog antibody 展开
Function :
Cdk1 is a small protein (approximately 34 kilodaltons), and is highly conserved. Cdk1 is comprised mostly by the bare protein kinase motif, which other protein kinases share. Cdk1, like other kinases, contains a cleft in which ATP fits. When bound to its cyclin partners, Cdk1 phosphorylation leads to cell cycle progression. Given its essential role in cell cycle progression, Cdk1 is highly regulated. Most obviously, Cdk1 is regulated by its binding with its cyclin partners. Cyclin binding alters access to the active site of Cdk1, allowing for Cdk1 activity; furthermore, cyclins impart specificity to Cdk1 activity. At least some cyclins contain a hydrophobic patch which may directly interact with substrates, conferring target specificity. Furthermore, cyclins can target Cdk1 to particular subcellular locations.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within N-terminal human CDk1.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IHC-P, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3069564
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃.{{Deucravacitinib} medchemexpress|{Deucravacitinib} Immunology/Inflammation|{Deucravacitinib} Biological Activity|{Deucravacitinib} In Vitro|{Deucravacitinib} custom synthesis|{Deucravacitinib} Epigenetic Reader Domain} Avoid repeated freeze / thaw cycles.{{Amivantamab} site|{Amivantamab} EGFR|{Amivantamab} Biological Activity|{Amivantamab} In Vitro|{Amivantamab} custom synthesis|{Amivantamab} Epigenetic Reader Domain}
Storage buffer solution:
1*PBS (pH7.PMID:24065671 4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 34 kDa
Positive control :
MCF-7 cell lysate, Jurkat cell lysate, PC12 cell lysate, HepG2 cell lysate, Hela cell lysate, NIH/3T3 cell lysate, Mouse liver tissue lysate, SKBR3 cell lysate, Hela, HepG2, MCF-7, rat spleen tissue, human tonsil tissue, human breast cancer tissue, mouse spleen tissue, Hela.