Product Name :
CDK6 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
CDK 6 antibody CDK6 antibody CDK6_HUMAN antibody Cell division protein kinase 6 antibody Crk 2 antibody Crk2 antibody Cyclin dependent kinase 6 antibody Cyclin-dependent kinase 6 antibody MGC59692 antibody p40 antibody 展开
Function :
CDK6 protein contains a catalytic core composed of a serine/threonine domain.This protein also contains an ATP-binding pocket, inhibitory and activating phosphorylation sites, a PSTAIRE-like cyclin-binding domain and an activating T-loop motif. CDK6 is involved in a positive feedback loop that activates transcription factors through a reaction cascade. CDK6 is important for the control of G1 to S phase transition. However, in recent years, new evidence proved that the presence of CDK6 is not essential for proliferation in every cell type, the cell cycle has a complex circuitry of regulation and the role of CDK6 might be more important in certain cell types than in others, where CDK4 or CDK2 can act as protein kinases compensating its role.{{EMPA} web|{EMPA} Orexin Receptor (OX Receptor)|{EMPA} Technical Information|{EMPA} In Vitro|{EMPA} supplier|{EMPA} Epigenetic Reader Domain}
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within residues of CDK6 aa 267-326 / 326.
Species reactivity:
Human, Green monkey, Mouse, Rat
Verify application:
WB, IF-Cell, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
AB_3069569
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.{{Rocuronium} medchemexpress|{Rocuronium} Membrane Transporter/Ion Channel|{Rocuronium} Biological Activity|{Rocuronium} References|{Rocuronium} manufacturer|{Rocuronium} Autophagy} Aliquot store at -20℃ or -80℃.PMID:23577779 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 37 kDa
Positive control :
Hela, HepG2, COS-1 cell lysate, K562 cell lysate, human colon cancer tissue, human breast cancer tissue.