Product Name :
(R)-Propranolol hydrochloride
Description:
(R)-Propranolol hydrochloride is a less active enantiomer of the β-adrenoceptor antagonist propranolol (HY-B0573). Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively.
CAS:
13071-11-9
Molecular Weight:
295.80
Formula:
C16H22ClNO2
Chemical Name:
(2R)-1-(naphthalen-1-yloxy)-3-[(propan-2-yl)amino]propan-2-ol; chlorohydrogen
Smiles :
Cl.CC(C)NC[C@@H](O)COC1C=CC=C2C=CC=CC2=1
InChiKey:
ZMRUPTIKESYGQW-PFEQFJNWSA-N
InChi :
InChI=1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H/t14-;/m1./s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.{{Lapatinib ditosylate} MedChemExpress|{Lapatinib ditosylate} Protein Tyrosine Kinase/RTK|{Lapatinib ditosylate} Biological Activity|{Lapatinib ditosylate} In stock|{Lapatinib ditosylate} supplier|{Lapatinib ditosylate} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
(R)-Propranolol hydrochloride is a less active enantiomer of the β-adrenoceptor antagonist propranolol (HY-B0573). Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist, has high affinity for the β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively.|Product information|CAS Number: 13071-11-9|Molecular Weight: 295.80|Formula: C16H22ClNO2|Chemical Name: (2R)-1-(naphthalen-1-yloxy)-3-[(propan-2-yl)amino]propan-2-ol; chlorohydrogen|Smiles: Cl.CC(C)NC[C@@H](O)COC1C=CC=C2C=CC=CC2=1|InChiKey: ZMRUPTIKESYGQW-PFEQFJNWSA-N|InChi: InChI=1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H/t14-;/m1./s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Diethylstilbestrol} site|{Diethylstilbestrol} Estrogen Receptor/ERR|{Diethylstilbestrol} Purity & Documentation|{Diethylstilbestrol} Description|{Diethylstilbestrol} manufacturer|{Diethylstilbestrol} Cancer} |Shelf Life: ≥12 months if stored properly.PMID:35901518 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|Both isomers of propranolol are capable of preventing adrenaline-induced cardiac arrhythmias in cats anaesthetized with halothane, but the mean dose of (-)-propranolol is 0.09 mg/kg whereas that of (+)-propranolol is 4.2 mg/kg. Both isomers of propranolol are capable of reversing ventricular tachycardia caused by ouabain in anaesthetized cats and dogs. The dose of (-)-propranolol is significantly smaller than that of (+)-propranolol ((R)-Propranolol) in both species. (R)-Propranolol hydrochloride (10 mg/kg) has no antagonistic activity in rats, the cardiac responses to isoprenaline of rat can be blocked by probably much less than 1/100th of that of the (-) isomer in this preparation.|Products are for research use only. Not for human use.|