Product Name :
CD80/B7-1 Recombinant Mouse Monoclonal Antibody [8-E5-R]
Predicted band size :
33 kDa
Observed band size :
60 kDa
Synonyms:
Activation B7-1 antigen antibody B lymphocyte activation antigen B7 antibody B7 antibody B7-1 antibody B7-1 antigen antibody B7.1 antibody BB1 antibody CD28 antigen ligand 1 antibody CD28LG antibody CD28LG1 antibody 展开
Function :
CD80/B7-1 is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. After engagement of T-cell receptor with antigen in association with major histocompatibility complex class II, a second signal mediated through the binding of B7 to CD28 greatly upregulates the production of multiple lymphokines. B7-1 is a costimulatory molecule for the activation of both CD4+ and CD8+ T lymphocytes that prevents the induction of clonal anergy. Thus, the transfer of B7-1 genes into tumor cells can induce protective immunity and lead to tumor rejection of some tumors in model systems of in vivo tumor growth.
Antibody Type:
Recombinant Mouse Monoclonal Antibody
Immunogen :
Synthetic peptide within human CD80 aa 74-118 / 288.
Species reactivity:
Human
Verify application:
WB
Coupling :
unconjugated
Clone number:
8-E5-R
RRID:
AB_3096763
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.{{Piperine} medchemexpress|{Piperine} Endogenous Metabolite|{Piperine} Purity & Documentation|{Piperine} In Vitro|{Piperine} custom synthesis|{Piperine} Epigenetic Reader Domain} Aliquot store at -20℃.{{Balovaptan} medchemexpress|{Balovaptan} GPCR/G Protein|{Balovaptan} Protocol|{Balovaptan} In Vivo|{Balovaptan} custom synthesis|{Balovaptan} Autophagy} Avoid repeated freeze / thaw cycles.PMID:23833812
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG1
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 33 kDa
Positive control :
Human brain tissue lysates.