transferrin fragment

Additional information:
Transferrin is the principal ironbinding protein in animal serum and is analogous in its iron-binding site and properties to lactoferrin1. Human transferrin is a single-chain glycoprotein of molecular weight near 80,000. The molecule is arranged in two lobes, each bearing a single metal-binding site. Although similar in ligand structure2, 3, the sites are distinguishable in many of their properties 4, 5. Sequence homology between the lobes6 and internal homology in organization of the transferrin gene7 establish that the modern protein arose by duplication and fusion of a primitive gene specifying a single-sited transferrin precursor protein. Each lobe of the transferrin molecule contains a recognition site for the chick receptor, and that both lobes are required for binding to receptor8. The receptor-binding activity of human transferrin is essentially confined to the C-terminal lobe and is preserved in the C-fragment even in the absence of the N-fragment.|Product information|Molecular Weight: 1824.97|Formula: C75H121N23O28S|Chemical Name: 4-{2-[2-(2-{2-[2-(2-aminopropanamido)-3-carboxypropanamido]-5-carbamimidamidopentanamido}-3-carboxypropanamido)-4-carbamoylbutanamido]-3-(4-hydroxyphenyl)propanamido}-4-({1-[(1-{[1-({1-[(1-{[1-({1-[(4-carbamimidamido-1-carboxybutyl)carbamoyl]-2-hydroxypropyl}carbamoyl)-2-carbamoylethyl]carbamoyl}-2-carboxyethyl)carbamoyl]-3-methylbutyl}carbamoyl)-2-sulfanylethyl]carbamoyl}-3-methylbutyl)carbamoyl]-3-methylbutyl}carbamoyl)butanoic acid|Smiles: CC(N)C(=O)NC(CC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(O)=O)C(=O)NC(CCC(N)=O)C(=O)NC(CC1C=CC(O)=CC=1)C(=O)NC(CCC(O)=O)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CS)C(=O)NC(CC(C)C)C(=O)NC(CC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NC(CCCNC(N)=N)C(O)=O|InChiKey: MAAMCHVQLWJBKY-UHFFFAOYSA-N|InChi: InChI=1S/C75H121N23O28S/c1-32(2)23-43(63(115)91-45(25-34(5)6)65(117)97-51(31-127)71(123)92-44(24-33(3)4)64(116)96-50(30-57(109)110)69(121)94-47(27-53(78)102)70(122)98-58(36(8)99)72(124)88-42(73(125)126)12-10-22-84-75(81)82)90-62(114)41(18-20-54(103)104)87-66(118)46(26-37-13-15-38(100)16-14-37)93-61(113)40(17-19-52(77)101)86-68(120)49(29-56(107)108)95-60(112)39(11-9-21-83-74(79)80)85-67(119)48(28-55(105)106)89-59(111)35(7)76/h13-16,32-36,39-51,58,99-100,127H,9-12,17-31,76H2,1-8H3,(H2,77,101)(H2,78,102)(H,85,119)(H,86,120)(H,87,118)(H,88,124)(H,89,111)(H,90,114)(H,91,115)(H,92,123)(H,93,113)(H,94,121)(H,95,112)(H,96,116)(H,97,117)(H,98,122)(H,103,104)(H,105,106)(H,107,108)(H,109,110)(H,125,126)(H4,79,80,83)(H4,81,82,84)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Namodenoson} web|{Namodenoson} Adenosine Receptor|{Namodenoson} Purity & Documentation|{Namodenoson} In Vitro|{Namodenoson} manufacturer|{Namodenoson} Epigenetic Reader Domain} |Shelf Life: ≥12 months if stored properly.PMID:25818744 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|