Product Name :
CD6 Mouse Monoclonal Antibody [12-D1]
Predicted band size :
Observed band size :
Synonyms:
CD_antigen=CD6 antibody CD6 antibody CD6 antigen Tp120 antibody CD6 molecule antibody CD6_HUMAN antibody FLJ44171 antibody OX52 antibody T cell differentiation antigen CD6 antibody T-cell differentiation antigen CD6 antibody T12 antibody 展开
Function :
CD6 is a type I transmembrane glycoprotein that is present on mature thymocytes, peripheral T cells and a subset of B cells. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T-cell activation and the size difference between the CD6 forms is due in part to differences in phosphorylation state. CD6 protein contains a 24-amino acid signal sequence, three extracellular “scavenger receptor cysteine-rich” (SRCR) domains, a membrane-spanning domain, and a 44-amino acid cytoplasmic domain. CD6 shows significant homology to CD5. CD6, which is also found in brain and B cell chronic lymphocytic leukemias, plays an important role in interactions of thymocytes with thymic epithelial cells. CD6 molecules can physically associate with the TCR/CD3 complex.S2116
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Purified recombinant fragment of human CD6 (AA: 18-199) expressed in E.Idarubicin hydrochloride Coli.PMID:26644518
Species reactivity:
Human
Verify application:
IHC-P, ICC, FC
Coupling :
unconjugated
Clone number:
12-D1
RRID:
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
4℃; -20℃ for long term storage.
Storage buffer solution:
Purified antibody in PBS with 0.05% sodium azide.
Subtype:
IgG2b
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
72 kDa
Positive control :
Human CD6 recombinant protein, CD6-hIgGFc transfected HEK293 cell lysate, human breast cancer tissue, human rectum cancer tissue, Hela.