Product Name :
CD48 Recombinant Rabbit Monoclonal Antibody [JE37-98]
Predicted band size :
27.7 kDa
Observed band size :
40 kDa
Synonyms:
Antigen CD48 antibody B cell membrane protein antibody B lymphocyte activation marker BLAST 1 antibody B-cell activation marker antibody B-lymphocyte activation marker BLAST-1 antibody BCM 1 surface antigen antibody BCM1 antibody BCM1 surface antigen antibody BLAST 1 antibody BLAST antibody 展开
Function :
CD48 is a glycosylphosphatidylinositol (GPI) -anchored membrane protein of the signaling lymphocyte activation molecule (SLAM) family, also known as SLAMF2 and BLAST-1. It is constitutively expressed on most hematopoietic cells (not on neutrophils and a subset of long-term hematopoietic stem cells in mice) and can be upregulated under certain conditions like infection. Interaction with its low affinity ligand CD2 promotes adhesion and TCR signaling. Interaction with the high affinity ligand CD244 (2B4) regulates natural killer (NK) and CD8 T cell activation and cytolytic function.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within Human CD48 aa 144-243 / 243.Anti-Mouse CD44 Antibody
Species reactivity:
Human
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
JE37-98
RRID:
AB_3072488
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Emixustat Aliquot store at -20℃.PMID:24238415 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 27.7 kDa
Positive control :
Raji cell lysate, Jurkat cell lysate, human colon tissue, human kidney tissue.