Product Name :
3mC Recombinant Rabbit Monoclonal Antibody [PSH03-21]
Predicted band size :
Observed band size :
Synonyms:
Function :
Methylation of DNA can occur non-enzymatically at the nitrogen-three of the cytosine base through spontaneous exposure to endogenous S-adenosyl methionine (SAM). The resulting 3-methylcytosine (3-mC) is mutagenic and must be repaired, which occurs in humans through the base excision repair (BER) or dealkylation via human homologues of the E. coli AlkB protein. 3-methylcytosine is present in human cell lines and increased levels of 3-mC impair proliferation.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
3-mc-OVA
Species reactivity:
Species independent
Verify application:
IF-Cell, Dot Blot
Coupling :
unconjugated
Clone number:
PSH03-21
RRID:
AB_3096497
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.NPX800 Aliquot store at -20℃.Olacaftor Avoid repeated freeze / thaw cycles.PMID:35991869
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Positive control :
U-2 OS cells treated with 4mM Methyl Methanesulfonate for 1 hour.