CD42b Recombinant Mouse Monoclonal Antibody [13G2-R]

Product Name :
CD42b Recombinant Mouse Monoclonal Antibody [13G2-R]

Predicted band size :

Observed band size :

Synonyms:
Antigen CD42b alpha antibody BDPLT1 antibody BDPLT3 antibody BSS antibody CD 42b antibody CD42b alpha antibody CD42B antibody CD42b antigen antibody DBPLT3 antibody GLYCOCALICIN antibody 展开

Function :
Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy.Baclofen

Antibody Type:
Recombinant Mouse Monoclonal Antibody

Immunogen :
Recombinant protein within human CD42b aa 100-350 / 652.Plitidepsin

Species reactivity:
Human

Verify application:
IHC-P

Coupling :
unconjugated

Clone number:
13G2-R

RRID:

Form :
Liquid

Concentration :
1ug/ul

Storage instructions:
Store at +4℃ after thawing.PMID:23991096 Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Subtype:
IgG1

Purification method :
Protein A affinity purified.

ELTSA :

Molecular weight :
Predicted band size: 72 kDa

Positive control :
Human bone marrow tissue, human spleen tissue.

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