CD40 Mouse Monoclonal Antibody [A1E6]

Product Name :
CD40 Mouse Monoclonal Antibody [A1E6]

Predicted band size :

Observed band size :

Synonyms:
AI326936 antibody B cell associated molecule CD40 antibody B cell surface antigen CD40 antibody B cell-associated molecule antibody B-cell surface antigen CD40 antibody Bp50 antibody CD 40 antibody CD40 antibody CD40 antigen (TNF receptor superfamily member 5) antibody CD40 antigen antibody 展开

Function :
This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Antibody Type:
Mouse Monoclonal Antibody

Immunogen :
Recombinant protein within human CD40 aa 1-250.Pramipexole dihydrochloride

Species reactivity:
Human

Verify application:
WB, IF-Cell, IHC-P

Coupling :
unconjugated

Clone number:
A1E6

RRID:
AB_3068885

Form :
Liquid

Concentration :
2ug/ul

Storage instructions:
Store at +4℃ after thawing.Tesofensine Aliquot store at -20℃.PMID:24834360 Avoid repeated freeze / thaw cycles.

Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Subtype:
IgG2b

Purification method :
Protein A affinity purified.

ELTSA :

Molecular weight :
Predicted band size: 31 kDa

Positive control :
Daudi cell lysates, MG-63, SiHa, SKOV-3, human tonsil tissue.

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