Product Name :
CD32 Recombinant Rabbit Monoclonal Antibody [JM10-70]
Predicted band size :
Observed band size :
Synonyms:
CD32 antibody CD32A antibody CD32B antibody CD32C antibody CDw32 antibody Fc fragment of IgG low affinity IIa receptor antibody Fc fragment of IgG low affinity IIa receptor for (CD32) antibody Fc fragment of IgG low affinity IIb receptor antibody Fc fragment of IgG low affinity IIb receptor for (CD32) antibody Fc fragment of IgG low affinity IIc receptor antibody 展开
Function :
CD32 (also designated Fc gamma RII) is a low affinity receptor for the Fc fragment of aggregated IgG. CD32 is responsible for the clearance of immunocomplexes by macrophages and also plays an important role in the regulation of antibody production by B cells. IgG can noncooperatively bind either one or two highly glycosylated CD32 molecules, and this binding delivers a negative signal for B cells . CD32 exists as several isoforms that are produced by alternative splicing of three distinct genes, A, B, and C .Atropine sulfate monohydrate These isoforms are designated FcgRIIA, FcgRIIB1, FcgRIIB3, and FcgRIIC . All isoforms are present on monocytes, placental trophoblasts and endothelial cells . In addition, the FcgRIIB forms are present on B lymphocytes, and the FcgRIIA and FcgRIIC forms are found on neutrophils.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within Human CD32 aa 23-274 / 310.
Species reactivity:
Human
Verify application:
WB, IHC-P, IF-Cell
Coupling :
unconjugated
Clone number:
JM10-70
RRID:
AB_3070400
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Glycitin Aliquot store at -20℃ or -80℃.PMID:34645436 Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 35 kDa
Positive control :
Human lung tissue lysates, human tonsil tissue, human spleen tissue, human pancreas tissue, K-562.