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TGFβ-IN-2
CAS No. : 2387678-02-4
Biological Activity：TGFβ-IN-2 (Compound 9d) inhibits TGF-β-induced total collagen accumulation in NRK-49F cells with the IC50 of 4.31 μM. TGFβ-IN-2 suppresses the TGF-β-induced protein expression of COL1A1, α-SMA, and p-Smad3 in vitro. TGFβ-IN-2 can be used as a potential effective compound for anti-fibrosis in vivo by oral administration.
Research Area：Inflammation/Immunology
Targets：TGF-beta/Smad
Related Small Molecules:SRI-011381;Ponsegromab;Isoviolanthin;ALK5-IN-32;Asiaticoside;Halofuginone hydrobromide;ALK5-IN-28;Oxymatrine;Trabedersen;CCT365623 hydrochloride;Butaprost;Disitertide TFA;ALK5-IN-34;Alantolactone;(E)-SIS3;Chebulinic acid;R-268712;Mongersen;EMT inhibitor-1;IDE 2;10,11-Dehydrocurvularin
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