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ITK antagonist
CAS No. : 1149753-56-9
Biological Activity：ITK antagonist (compound 10 n) is a potent, orally active and selective ITK (Interleukin-2 inducible T-cell kinase) antagonist (IC50=1 and 20 nM in different assays). ITK antagonist inhibits insulin receptor kinase (IRK) with an IC50 of 160 nM.
Research Area：Inflammation/Immunology
Targets：Itk
Related Small Molecules:Vecabrutinib;EGFR-IN-40;GSK-2250665A;ITK/TRKA-IN-1;ITK inhibitor 2;ITK inhibitor 5;PF-06465469;PRN694;BI-1622;BMS-509744;ITK inhibitor 6;GNE-4997
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