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hCAIX-IN-8

CAS No. : 2414633-40-0

Biological Activity：hCAIX-IN-8 (compound 7i) is a potent and selective hCAIX inhibitor with IC₅₀s of 1.99, 0.024, 1.10 µM for CAII, CAIX, CAVA respectively. hCAIX-IN-8 shows anti-proliferation activity with low toxicity. hCAIX-IN-8 decreases the epithelial to mesenchymal transitions and induces apoptosis. hCAIX-IN-8 inhibits cell migration and colonization potential.

Research Area：Cancer

Targets：Carbonic Anhydrase

Related Small Molecules:Enpp/Carbonic anhydrase-IN-1;Phenylsulfamide;Benzolamide;(E)-Dehydrodiconiferyl alcohol;hCAIX/XII-IN-1;CAXII-IN-1;hCAIX/XII-IN-2;hCAIX-IN-12;Girentuximab;hCAII-IN-2;hCAI/II-IN-1;hCAI/II-IN-4;Dichlorphenamide;hCAIX-IN-16;hCAII-IN-1;Sultiame;hCAII-IN-3;Carbonic anhydrase inhibitor 6;hCAXII-IN-4;hCAIX-IN-10;U-104;Carbonic anhydrase inhibitor 4;EMAC10101d

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