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GRL-0496

CAS No. : 1087243-14-8

Biological Activity：GRL-0496 is a potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitor, with an IC₅₀ of 30 nM in both enzyme inhibitory and antiviral assays. GRL-0496 shows SARS-CoV antiviral activity, with an EC₅₀ of 6.9 μM.

Research Area：Infection

Targets：SARS-CoV

Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection Compound Library;Antiviral Compound Library;

Related Small Molecules:SARS-CoV-2-IN-33;Grazoprevir potassium salt;SARS-CoV-2-IN-19;Molnupiravir;SARS-CoV-2 Mpro-IN-3;MM3122;Ketotifen fumarate;SARS-CoV-2-IN-16;Thapsigargin;INSCoV-614(1B);Anti-SARS-CoV-2 Spike mAb (CR3022);GNF-2;Bemnifosbuvir hemisulfate;Kansuinine B;Proglumetacin;HCoV-229E-IN-1

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