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Retinoic acid
CAS No. : 302-79-4
Biological Activity：Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.
Research Area：Cancer
Targets：Autophagy|RAR/RXR|PPAR|Endogenous Metabolite
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