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LDN-211904 oxalate
CAS No. : 1198408-78-4
Biological Activity：LDN-211904 oxalate (compound 32) is a potent and selective EphB3 inhibitor with an IC50 of 0.079 µM. LDN-211904 oxalate shows good metabolic stability in mouse liver microsomes. LDN-211904 oxalate with cetuximab could be effective in inhibiting STAT3-activated CSC stemness and cetuximab resistance in CRC[2].
Research Area：Cancer
Targets：Ephrin Receptor
Related Small Molecules:KYL peptide;UniPR129;EphA2 agonist 2;ALW-II-41-27;Targefrin;JI-101;Eph inhibitor 2;UniPR505;ML786 dihydrochloride;NVP-BHG712;Tesevatinib;BT5528;123C4;EphA2 agonist 1
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