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AGI-12026
CAS No. : 1446501-77-4
Biological Activity：AGI-12026 is brain-penetrant dual inhibitor of mutant IDH1 and 2. AGI-12026 shows partial inhibition of the IDH1-R132H homodimer as allosteric modulators. AGI-12026 has the potential for research of glioma.
Research Area：Neurological Disease
Targets：Isocitrate Dehydrogenase (IDH)
Related Small Molecules:mIDH1-IN-1;Enasidenib mesylate;IDH1 Inhibitor 2;DS-1001b;BAY-1436032;Mutant IDH1-IN-1;(R,S)-Ivosidenib;AGI-5198;IDH-C227;IDH1 Inhibitor 1;AGI-6780;Mutant IDH1-IN-6;Olutasidenib;IDH-305;IDH1 Inhibitor 3;IDH2R140Q-IN-1;Vorasidenib;(S,R)-GSK321;IDH889;IDH1 Inhibitor 5;Mutant IDH1 inhibitor;Mutant IDH1-IN-2;Mutant IDH1-IN-4;GSK864
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