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JNJ-47965567

CAS No. : 1428327-31-4

Biological Activity：JNJ-47965567 is a centrally permeable, high-affinity, selective P2X7 antagonist, with pK_is of 7.9 and 8.7 for human and rat P2X7, respectively. JNJ-47965567 can be used to probe the role of central P2X7 in rodent models of CNS pathophysiology.

Research Area：Neurological Disease

Targets：P2X Receptor

Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Covalent Screening Library;Pyroptosis Compound Library;Neurotransmitter Receptor Compound Library;Targeted Diversity Library;

Related Small Molecules:Gefapixant citrate;AF-353;Oxatomide;AZ10606120 dihydrochloride;Taspine;A-317491;NF449 octasodium;A-804598;P2X receptor-1;Aurintricarboxylic acid;Minodronic acid;NF023 hexasodium;A 438079 hydrochloride;KN-62;Opiranserin;GW791343 dihydrochloride;5-BDBD;NF279;Lu AF27139;JNJ-55308942;PPNDS tetrasodium;8-Bromo-ATP;P2X3 antagonist 36;NF110;BAY-1797;Ro-51;P2X3 antagonist 37

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