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Savolitinib

CAS No. : 1313725-88-0

Biological Activity：Savolitinib (AZD-6094) is a potent, highly selective, and orally bioavailable c-Met inhibitor with IC₅₀ s of 5 nM and 3 nM for c-Met and p-Met, respectively. Savolitinib (AZD-6094) selectively binds to and inhibits the activation of c-Met in an ATP-competitive manner, and disrupts c-Met signal transduction pathways. Antineoplastic activity^[2].

Research Area：Cancer

Targets：c-Met/HGFR

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Drug Repurposing Compound Library;Anti-COVID-19 Compound Library;NMPA-Approved Drug Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Lung Cancer Compound Library;Angiogenesis-Related Compound Library;Targeted Diversity Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;FDA-Approved Anticancer Drug Library;Anti-Prostate Cancer Compound Library;Cancer Stem Cells Compound Library;

Related Small Molecules:AMG-208;D6808;MET kinase-IN-2;c-Met-IN-9;Tyrosine kinase-IN-4;Foretinib;PF-04217903 phenolsulfonate;MK-2461;XL092;SAR125844;MK-8033 hydrochloride;BPI-9016M;Ficlatuzumab;Meleagrin;c-Met inhibitor 1;Pamufetinib;PHA-665752;c-Met/HDAC-IN-2;SU11274;Antitumor agent-45;Capmatinib hydrochloride;SCR-1481B1;SYN1143;Amuvatinib hydrochloride;c-Met/HDAC-IN-3;Gemnelatinib

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