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NL-1
CAS No. : 188532-26-5
Biological Activity：NL-1 is a mitoNEET inhibitor with antileukemic effect. NL-1 inhibits REH and REH/Ara-C cells growth with IC50s of 47.35 µM and 56.26 µM, respectively. NL-1-mediated death in leukemic cells requires the activation of the autophagic pathway.
Research Area：Cancer
Targets：Autophagy|Mitochondrial Metabolism
Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Reprogramming Compound Library;Glutamine Metabolism Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Mitochondria-Targeted Compound Library;Glucose Metabolism Compound Library;Cuproptosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:MitoTam bromide, hydrobromide;MitoTEMPO hydrate;Thiabendazole-d4;D-Histidine;Mito-apocynin (C2);Fumarate hydratase-IN-2 sodium salt;Schaftoside;Daidzin;Azemiglitazone;Tempo;Idebenone;Menadiol;CTPI-2;Senecionine acetate;Antimalarial agent 14;Mito-apocynin (C11);OXPHOS-IN-1;Mitochondrial respiration-IN-1 hydrobromide;Tubulin/HDAC-IN-1;Clidanac;IMT1;Nonactin;RYL-552;DX2-201;MSDC 0160
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