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Derenofylline
CAS No. : 251945-92-3
Biological Activity：Derenofylline (SLV 320) is a potent, selective and orally active adenosine A1 receptor antagonist, with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively. Derenofylline suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats.
Research Area：Cardiovascular Disease
Targets：Adenosine Receptor
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Clinical Compound Library;Small Molecule Immuno-Oncology Compound Library;Drug Repurposing Compound Library;Anti-Cardiovascular Disease Compound Library;Orally Active Compound Library;Neurotransmitter Receptor Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;
Related Small Molecules:MRS 1523;APNEA;MIPS521;FSCPX;Theobromine-d3;Inosine-13C;Norisoboldine;N-0861 racemate;Xanthine amine congener dihydrochloride;LUF6096;A1/A3 AR antagonist 1;ATL-801;Istradefylline;Doxofylline-d6;A1AR antagonist 3;MRS1186;A2A/A3 AR antagonist-1;A2AAR/HDAC-IN-2;MRS-1191;MRS5698;GP531;Imaradenant;PSB-0788
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