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Mifobate
CAS No. : 76541-72-5
Biological Activity：Mifobate (SR-202) is a potent and specific PPARγ antagonist. Mifobate (SR-202) selectively inhibits Thiazolidinedione (TZD)-induced PPARγ transcriptional activity (IC50=140 μM). Mifobate (SR-202) does not affect basal or ligand-stimulated transcriptional activity of PPARα, PPARβ, or the farnesoid X receptor (FXR). Mifobate (SR-202) shows antiobesity and antidiabetic effects.
Research Area：Metabolic Disease
Targets：PPAR
Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Anti-Aging Compound Library;Anti-diabetic Compound Library;Anti-Obesity Compound Library;Transcription Factor-Targeted Library;Lipid Metabolism Compound Library ;Nuclear Receptor Compound Library;
Related Small Molecules:Falcarindiol;5-Aminosalicylic Acid-D3 hydrochloride;Retinoic acid;PPARγ agonist 7;Licarin B;Daidzein-d4;Ciglitazone;MK-886;CP-775146;FK614;Muraglitazar;Magnolol;PPAR agonist 1;PPARα agonist 1;PPARγ phosphorylation inhibitor 1;GSK0660;Glabridin;CUDA;Norathyriol;Saroglitazar;GW 9578;Elafibranor;ST247;Bilobetin
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