SJ10542

For research use only. We do not sell to patients.

SJ10542

Biological Activity:SJ10542 is a potent and selective JAK2/3 directing phenyl glutarimide (PG)-PROTAC with DC50s of 14, 11, and 24 nM for JAK2, JAK3, and JAK2-fusion ALL, respectively. SJ10542 utilizes a PG ligand as the cereblon (CRBN) recruiter.

Research Area:Cancer|Inflammation/Immunology

Targets:JAK|PROTACs

Related Screening Libraries:Bioactive Compound Library Plus;

Related Small Molecules:AZ-3;PROTAC Sirt2 Degrader-1;DB0614;JAK3/BTK-IN-1;AT9283;Benzene hexabromide;PROTAC VEGFR-2 degrader-2;(E/Z)-Zotiraciclib;dTAGV-1-NEG;CCT367766 formic;JAK-IN-10;Baricitinib-d3;JAK3-IN-6;HDAC6 degrader-1;PROTAC Axl Degrader 2;PhosTAC7;MS98;JPS014;Coumermycin A1;Deucravacitinib;PROTAC PARP1 degrader;MD-224;Momelotinib-3,3,5,5-d4;FKBP12 PROTAC dTAG-7;MS8815;RIP2 Kinase Inhibitor 4

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