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Olverembatinib

CAS No. : 1257628-77-5

Biological Activity：Olverembatinib (GZD824) is a potent and orally active pan-Bcr-Abl inhibitor. Olverembatinib potently inhibits a broad spectrum of Bcr-Abl mutants. Olverembatinib strongly inhibits native Bcr-Abl and Bcr-Abl^T315I with IC₅₀s of 0.34 nM and 0.68 nM, respectively. Olverembatinib has antitumor activity.

Research Area：Cancer

Targets：Bcr-Abl

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Kinase Inhibitor Library; Protein Tyrosine Kinase Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Drug Repurposing Compound Library;NMPA-Approved Drug Library;Cytoskeleton Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Alzheimer’s Disease Compound Library;Anti-Blood Cancer Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Rare Diseases Drug Library;FDA-Approved Anticancer Drug Library;

Related Small Molecules:AT9283;Bafetinib;Pivanex;SNIPER(ABL)-039;Flumatinib mesylate;IHMT-TRK-284;SNIPER(ABL)-049;GNF-2;CT-721;SNIPER(ABL)-015;GNF-5;BCR-ABL-IN-4;SNIPER(ABL)-033;CHMFL-ABL-039;BCR-ABL-IN-6;c-ABL-IN-2;SNIPER(ABL)-058;ON 146040;HG-7-85-01;CHMFL-ABL/KIT-155;Radotinib-d6;BCR-ABL-IN-1;SIAIS178

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