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Taltobulin
CAS No. : 228266-40-8
Biological Activity：Taltobulin (HTI-286), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis.
Research Area：Cancer
Targets：Microtubule/Tubulin|ADC Cytotoxin|Apoptosis
Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;Toxins for Antibody-Drug Conjugate Research Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Cytoskeleton Compound Library;Anti-Lung Cancer Compound Library;Anti-Blood Cancer Compound Library;Protein-protein Interaction Inhibitor Library;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;Sandramycin;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;Tirbanibulin dihydrochloride;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Tilavonemab;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib
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