For research use only. We do not sell to patients.
Temuterkib
CAS No. : 1951483-29-6
Biological Activity：Temuterkib (LY3214996) is a highly selective inhibitor of ERK1 and ERK2, with IC50 of 5 nM for both enzymes in biochemical assays. Temuterkib potently inhibits cellular p-RSK1 in BRAF and RAS mutant cancer cell lines. Temuterkib shows potent antitumor activities in cancer models with MAPK pathway alterations.
Research Area：Cancer
Targets：ERK
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;MAPK Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Glutamine Metabolism Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Corynoxeine;CKLF1-C27;LM22B-10;ERK5-IN-4;Pachymic acid;MAP855;6-OAU;VX-11e;Pluripotin;2,5-Dihydroxyacetophenone;Astragaloside IV;ERK1/2 inhibitor 1;Longdaysin;[Tyr8] Bradykinin;Gypenoside L;ERK-IN-2;Omtriptolide;Chemerin-9 (149-157);MAPK-IN-1;SHR2415;Anti-inflammatory agent 31;PACAP-38 (31-38), human, mouse, rat TFA;AKT-IN-11;N-Salicyloyltryptamine;JWG-071
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
About Us:
- MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
- Structurally and synthetically diverse biologically active compounds；
- roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
- We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
- Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；
- Customized order volume ranging from milligrams to kilograms scale；
Structurally and synthetically diverse biologically active compounds；
We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.
