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MK-3207 Hydrochloride

CAS No. : 957116-20-0

Biological Activity：MK-3207 (Hydrochloride) is a potent and orally bioavailable CGRP receptor antagonist with IC₅₀ of 0.12 nM and K_i of 0.024 nM, and is highly selective versus human AM1, AM2, CTR, and AMY3.

Research Area：Neurological Disease

Targets：CGRP Receptor

Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;Clinical Compound Library;Orally Active Compound Library;Targeted Diversity Library;

Related Small Molecules:Vazegepant hydrochloride;Adrenomedullin (16-31), human;α-CGRP, rat;Cagrilintide acetate;HTL22562;SUN B8155;Adrenomedullin (11-50), rat;Rat CGRP-(8-37);Atogepant;β-CGRP, human TFA;Calcitonin (salmon);Calcitonin (human);α-CGRP(human);Galcanezumab;Olcegepant;Rimegepant;Calcitonin Gene Related Peptide (CGRP) II, rat;Ubrogepant;PHM-27 (human);Adrenomedullin (1-50), rat;CGRP antagonist 1;Telcagepant;HCGRP-(8-37)

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